Retropharyngeal abcess is an abcess located behind the posterior pharyngeal wall in the retropharyngeal space. Retropharyngeal abcess is difficult to diagnose by physical examination because they are located in the deep tissue spaces. The patient usually presents with stiff neck and difficulty in swallowing. As the deep spaces in neck are continuous with one another, the abcess can pass from the parapharyngeal space to the retropharyngeal space and then behind the esophagus into the mediastinum.
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Large Retropharyngeal Abscess

Image: “Large retropharyngeal abscess.” by James Heilman, MD – Own work. License: CC BY-SA 4.0


Pathophysiology of Pediatric Retropharyngeal Abscess

The retropharyngeal space, as the name suggests, lies behind the pharynx. It is bounded anteriorly by the buccopharyngeal fascia, posteriorly by the prevertebral fascia and laterally by the carotid sheaths. Superiorly it extends to the base of the skull and inferiorly to the mediastinum.

Epidemiology of Pediatric Retropharyngeal Abscess

A review conducted in Children’s Hospital of Michigan showed a 4.5 increase in the cases of retropharyngeal abcess over the past few years. Similarly different studies conducted in different hospitals in United State showed an increase in the cases of retropharyngeal abcess over time.

Worldwide, the incidence has reportedly been increasing due to late diagnosis and treatment. It is usually common in children under 5 years of age and its possible cause can be attributed to poor dental hygiene and dental infections.

Retropharyngeal abcess is less common in females and is more prevalent among males.

Signs and Symptoms of Pediatric Retropharyngeal Abscess

  • Stiff neck or torticollis
  • Severe pain in the neck
  • Malaise
  • Fever
  • Drooling of saliva
  • Enlarged cervical lymph nodes

Causes and Diagnosis of Pediatric Retropharyngeal Abscess

Disease is caused by aerobic as well as anaerobic organisms. Aerobic organisms include staphylococcus aureus and beta hemolytic streptococci. Anaerobic organisms include bacteroides and veillonella. Gram negative organisms include haemophilus parainfluenzae and bartonella henselae.

As the infection is present in the deep spaces, definitive diagnosis is made by CT scan. Lateral neck radiograph shows the presence of infection in approximately 80 % of the cases. Retropharyngeal abcess is suspected in cases where the retropharyngeal space is half of the size of second cervical vertebra.

Treatment of Pediatric Retropharyngeal Abscess

Definitive treatment is surgical incision of the abcess and ultimately drainage. The procedure is usually carried out without general anesthesia as intubation can rupture the abcess leading to aspiration into the lungs.

Some severe cases may require emergency tracheostomy. The disease requires the administration of high dose of intravenous antibiotics. Chronic cases of retropharyngeal abcess usually occurs secondary to tuberculosis and requires antitubercular therapy.

Complications

  • Aspiration of pus contents into the lungs
  • Airway obstruction
  • Mediastinitis
  • Osteomyelitis
  • Pericarditis
  • Jugular vein thrombosis

Mortality and morbidity

Mortality rate was 1 % in a review of neck space infections carried out in Taiwan. With the development of mediastinitis, the mortality can reach up to 50 % even after being treated by antibiotics. Retropharyngeal abcess can also cause jugular vein thrombosis, pericarditis and carotid artery erosion.

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