Rheumatoid arthritis Arthritis Acute or chronic inflammation of joints. Osteoarthritis (RA) is a symmetric, inflammatory polyarthritis and chronic, progressive, autoimmune disorder Autoimmune Disorder Septic Arthritis. Presentation Presentation The position or orientation of the fetus at near term or during obstetric labor, determined by its relation to the spine of the mother and the birth canal. The normal position is a vertical, cephalic presentation with the fetal vertex flexed on the neck. Normal and Abnormal Labor occurs most commonly in middle-aged women with joint swelling Swelling Inflammation, pain Pain An unpleasant sensation induced by noxious stimuli which are detected by nerve endings of nociceptive neurons. Pain: Types and Pathways, and morning stiffness (often in the hands). Systemic inflammation Systemic Inflammation Surgical Site Infections can lead to extraarticular manifestations such as rheumatoid nodules, interstitial lung disease, Felty syndrome, and pericarditis Pericarditis Pericarditis is an inflammation of the pericardium, often with fluid accumulation. It can be caused by infection (often viral), myocardial infarction, drugs, malignancies, metabolic disorders, autoimmune disorders, or trauma. Acute, subacute, and chronic forms exist. Pericarditis. Prolonged and severe disease can lead to irreversible joint deformities. Diagnosis is based on strong clinical suspicion and confirmed by the presence of rheumatoid factor Rheumatoid factor Antibodies found in adult rheumatoid arthritis patients that are directed against gamma-chain immunoglobulins. Autoimmune Hepatitis (RF), anti-cyclic citrullinated peptide (anti-CCP) antibodies Antibodies Immunoglobulins (Igs), also known as antibodies, are glycoprotein molecules produced by plasma cells that act in immune responses by recognizing and binding particular antigens. The various Ig classes are IgG (the most abundant), IgM, IgE, IgD, and IgA, which differ in their biologic features, structure, target specificity, and distribution. Immunoglobulins: Types and Functions, and characteristic imaging. Management involves long-term disease-modifying antirheumatic drugs Disease-modifying antirheumatic drugs Disease-modifying antirheumatic drugs are antiinflammatory medications used to manage rheumatoid arthritis. The medications slow, but do not cure, the progression of the disease. The medications are classified as either synthetic or biologic agents and each has unique mechanisms of action and side effects. Disease-Modifying Antirheumatic Drugs (DMARDs) ( DMARDs DMARDs Disease-modifying antirheumatic drugs are antiinflammatory medications used to manage rheumatoid arthritis. The medications slow, but do not cure, the progression of the disease. The medications are classified as either synthetic or biologic agents and each has unique mechanisms of action and side effects. Disease-Modifying Antirheumatic Drugs (DMARDs)), biologic agents Biologic Agents Immunosuppressants, and physical therapy Physical Therapy Becker Muscular Dystrophy. Glucocorticoids Glucocorticoids Glucocorticoids are a class within the corticosteroid family. Glucocorticoids are chemically and functionally similar to endogenous cortisol. There are a wide array of indications, which primarily benefit from the antiinflammatory and immunosuppressive effects of this class of drugs. Glucocorticoids and nonsteroidal antiinflammatory drugs Nonsteroidal Antiinflammatory Drugs Nonsteroidal antiinflammatory drugs (NSAIDs) are a class of medications consisting of aspirin, reversible NSAIDs, and selective NSAIDs. NSAIDs are used as antiplatelet, analgesic, antipyretic, and antiinflammatory agents. Nonsteroidal Antiinflammatory Drugs (NSAIDs) ( NSAIDs NSAIDS Primary vs Secondary Headaches) are the treatment of choice for acute exacerbation.
Last updated: 26 Nov, 2021
Rheumatoid arthritis Arthritis Acute or chronic inflammation of joints. Osteoarthritis (RA) diagnosis is based on high clinical suspicion and confirmed by serology Serology The study of serum, especially of antigen-antibody reactions in vitro. Yellow Fever Virus and imaging.
The goal is to prevent deformity Deformity Examination of the Upper Limbs and permanent damage. Patients Patients Individuals participating in the health care system for the purpose of receiving therapeutic, diagnostic, or preventive procedures. Clinician–Patient Relationship should be referred to a rheumatologist.
Acute exacerbation management:
Long-term pharmacological therapy:
Complement your med school studies with Lecturio’s all-in-one study companion, delivered with evidence-based learning strategies.
Lecturio Premium gives you full access to all content & features
Verify your email now to get a free trial.
Lecturio Premium gives you full access to all contents and features—including Lecturio’s Qbank with up-to-date board-style questions.