Ear: Anatomy

Embryology of the Ear

Development of the ear begins at 3 weeks of gestation and is usually complete by 20 weeks of gestation.

Inner ear

• Ectoderm Ectoderm The outer of the three germ layers of an embryo. Gastrulation and Neurulation overlying the rhombencephalon Rhombencephalon The posterior of the three primitive cerebral vesicles of an embryonic brain. It consists of myelencephalon, metencephalon, and isthmus rhombencephalon from which develop the major brain stem components, such as medulla oblongata from the myelencephalon, cerebellum and pons from the metencephalon, with the expanded cavity forming the fourth ventricle. Development of the Nervous System and Face thickens to form the otic placode. 
• The otic placode invaginates to become the otic pit. 
• The otic pit detaches from surface ectoderm Ectoderm The outer of the three germ layers of an embryo. Gastrulation and Neurulation to form the otic vesicle Vesicle Primary Skin Lesions.  
• The otic vesicle Vesicle Primary Skin Lesions divides into dorsal and ventral compartments. 
  • Dorsal compartment gives rise to:
    • Semicircular canals Semicircular canals Three long canals (anterior, posterior, and lateral) of the bony labyrinth. They are set at right angles to each other and are situated posterosuperior to the vestibule of the bony labyrinth (vestibular labyrinth). The semicircular canals have five openings into the vestibule with one shared by the anterior and the posterior canals. Within the canals are the semicircular ducts. Auditory and Vestibular Pathways: Anatomy
    • Utricle Utricle A membranous sac within the vestibular labyrinth of the inner ear. The utricle communicates with the saccule through the utriculosaccular duct from which the endolymphatic duct arises. The utricle and saccule have sensory areas (acoustic maculae) which are innervated by the vestibular nerve. Auditory and Vestibular Pathways: Anatomy
    • Endolymphatic appendage/sac
  • Ventral compartment gives rise to:
    • Cochlea
    • Spiral Spiral Computed tomography where there is continuous x-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures. Computed Tomography (CT) of the cochlea
• Otic vesicle Vesicle Primary Skin Lesions is filled with endolymph Endolymph The lymph fluid found in the membranous labyrinth of the ear. Vertigo, with surrounding mesenchyme that hollows out to create spaces filled with perilymph.
• Perilymph spaces become the scala tympani and scala vestibuli.
• Neural crest Neural crest The two longitudinal ridges along the primitive streak appearing near the end of gastrulation during development of nervous system (neurulation). The ridges are formed by folding of neural plate. Between the ridges is a neural groove which deepens as the fold become elevated. When the folds meet at midline, the groove becomes a closed tube, the neural tube. Hirschsprung Disease–derived cells → statoacoustic ganglion → cranial nerve (CN) VIII

Middle ear Middle ear The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. Acute Otitis Media

• Develops from the 3 germinal layers
• Auditory tube extends from the 1st pharyngeal pouch.
• 1st and 2nd pharyngeal arches Pharyngeal arches The branchial arches, also known as pharyngeal or visceral arches, are embryonic structures seen in the development of vertebrates that serve as precursors for many structures of the face, neck, and head. These arches are composed of a central core of mesoderm, which is covered externally by ectoderm and internally by endoderm. Branchial Apparatus and Aortic Arches give rise to the malleus, incus, and stapes.
• Auditory tube surrounds the ossicles → tympanic cavity
• Tympanic membrane
  • Inner layer ( endoderm Endoderm The inner of the three germ layers of an embryo. Gastrulation and Neurulation) 
  • Middle layer ( mesoderm Mesoderm The middle germ layer of an embryo derived from three paired mesenchymal aggregates along the neural tube. Gastrulation and Neurulation) 
  • Outer layer ( ectoderm Ectoderm The outer of the three germ layers of an embryo. Gastrulation and Neurulation)

Outer ear

• Groove between 1st and 2nd pharyngeal arches Pharyngeal arches The branchial arches, also known as pharyngeal or visceral arches, are embryonic structures seen in the development of vertebrates that serve as precursors for many structures of the face, neck, and head. These arches are composed of a central core of mesoderm, which is covered externally by ectoderm and internally by endoderm. Branchial Apparatus and Aortic Arches → external acoustic meatus
• Pharyngeal arches Pharyngeal arches The branchial arches, also known as pharyngeal or visceral arches, are embryonic structures seen in the development of vertebrates that serve as precursors for many structures of the face, neck, and head. These arches are composed of a central core of mesoderm, which is covered externally by ectoderm and internally by endoderm. Branchial Apparatus and Aortic Arches → auricular hillocks → external ear/auricle

Outer Ear Anatomy

Auricle

The auricle is composed of musculocutaneous tissue and elastic Elastic Connective Tissue: Histology cartilage Cartilage Cartilage is a type of connective tissue derived from embryonic mesenchyme that is responsible for structural support, resilience, and the smoothness of physical actions. Perichondrium (connective tissue membrane surrounding cartilage) compensates for the absence of vasculature in cartilage by providing nutrition and support. Cartilage: Histology covered by skin Skin The skin, also referred to as the integumentary system, is the largest organ of the body. The skin is primarily composed of the epidermis (outer layer) and dermis (deep layer). The epidermis is primarily composed of keratinocytes that undergo rapid turnover, while the dermis contains dense layers of connective tissue. Skin: Structure and Functions. This structure is responsible for collecting and redirecting sound waves into the external auditory meatus.

• Helix: curved outer rim 
• Antihelix: inner curved rim
• Tragus Tragus Otitis Externa and antitragus: protrusions that partially obstruct external auditory meatus
• Concha: hollow region in front of external auditory meatus 
• Lobule: inferior, fleshy portion of ear
• Triangular fossa: concave surface of anterosuperior ear
• Scaphoid fossa: concave surface of posterosuperior ear

External auditory meatus

The external auditory meatus is typically 1 in. (2.5 cm) in length and is S-shaped.

• Lateral ⅓ surrounded by cartilage Cartilage Cartilage is a type of connective tissue derived from embryonic mesenchyme that is responsible for structural support, resilience, and the smoothness of physical actions. Perichondrium (connective tissue membrane surrounding cartilage) compensates for the absence of vasculature in cartilage by providing nutrition and support. Cartilage: Histology (posterosuperior trajectory) 
• Medial ⅔ surrounded by temporal bone Temporal bone Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull). Jaw and Temporomandibular Joint: Anatomy (anteroinferior trajectory)
• Surrounding skin Skin The skin, also referred to as the integumentary system, is the largest organ of the body. The skin is primarily composed of the epidermis (outer layer) and dermis (deep layer). The epidermis is primarily composed of keratinocytes that undergo rapid turnover, while the dermis contains dense layers of connective tissue. Skin: Structure and Functions contains ceruminous and sebaceous glands → ear wax

Tympanic membrane

Transmits sound waves from the air to the ossicles → mechanical vibrations

• Located between outer and middle ear Middle ear The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. Acute Otitis Media 
• Attached to fibrocartilaginous ring of temporal bone Temporal bone Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull). Jaw and Temporomandibular Joint: Anatomy
• 3 layers: cutaneous, fibrous Fibrous Fibrocystic Change, and mucous 
• Ossicles attach to the tympanic membrane at the umbo.

Middle Ear

Tympanic cavity

• Bony membranous cavity shaped like a 6-sided prism and filled with air
• Contains the ossicles, muscles, and nerves
• The roof consists of the tegmental wall, which separates the malleus and incus from the middle cranial fossa Middle cranial fossa The compartment containing the anterior extremities and half the inferior surface of the temporal lobes (temporal lobe) of the cerebral hemispheres. Lying posterior and inferior to the anterior cranial fossa, it is formed by part of the temporal bone and sphenoid bone. It is separated from the posterior cranial fossa by crests formed by the superior borders of the petrous parts of the temporal bones. Skull: Anatomy.
• Labyrinthine or medial wall contents:
  • Oval window (connects to vestibule of the internal ear)
  • Round window (secondary tympanic membrane) 
  • Promontory
  • Prominence of the facial canal
• Relations:
  • Lateral wall: tympanic membrane
  • Posterior wall: 
    • Mastoid antrum
    • Communicates with mastoid air cells
  • Anterior wall (carotid wall): 
    • Thin layer of bone Bone Bone is a compact type of hardened connective tissue composed of bone cells, membranes, an extracellular mineralized matrix, and central bone marrow. The 2 primary types of bone are compact and spongy. Bones: Structure and Types separating the cavity from the carotid artery
    • Pierced by the tympanic branch of the internal carotid artery Internal carotid artery Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose. Carotid Arterial System: Anatomy and deep petrosal nerve
    • Contains the auditory tube
  • Floor (jugular wall): separates the cavity from the internal  jugular vein
• Auditory ossicles:
  • Amplify sound waves and transmit them to the labyrinth of the inner ear
  • Connect the tympanic membrane to the oval window
  • Smallest bones in the human body
  • Lateral → medial: malleus, incus, stapes

Muscles of the middle ear Middle ear The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. Acute Otitis Media

Middle ear Middle ear The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. Acute Otitis Media muscles are responsible for movement of the tympanic membrane.

• Tensor tympani muscle:
  • Origin:
    • Cartilaginous part of eustachian tube
    • Greater wing of the sphenoid
    • Semicanal for tensor tympani (petrous part of temporal bone Temporal bone Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull). Jaw and Temporomandibular Joint: Anatomy)
  • Insertion: superior part of the handle of the malleus
  • Innervation: mandibular branch of the trigeminal nerve Trigeminal nerve The 5th and largest cranial nerve. The trigeminal nerve is a mixed motor and sensory nerve. The larger sensory part forms the ophthalmic, mandibular, and maxillary nerves which carry afferents sensitive to external or internal stimuli from the skin, muscles, and joints of the face and mouth and from the teeth. Most of these fibers originate from cells of the trigeminal ganglion and project to the trigeminal nucleus of the brain stem. The smaller motor part arises from the brain stem trigeminal motor nucleus and innervates the muscles of mastication. The 12 Cranial Nerves: Overview and Functions (CN V3)
  • Function:
    • Pulls the handle of the malleus medially 
    • Tenses the tympanic membrane
• Stapedius muscle:
  • Origin: cartilaginous/bony margins of eustachian tube
  • Insertion: neck Neck The part of a human or animal body connecting the head to the rest of the body. Peritonsillar Abscess of stapes
  • Innervation: facial nerve Facial nerve The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and salivary glands, and convey afferent information for taste from the anterior two-thirds of the tongue and for touch from the external ear. The 12 Cranial Nerves: Overview and Functions (CN VII)
  • Function:
    • Pulls stapes posteriorly  
    • Prevents excessive oscillation of the ossicles

Eustachian tube (auditory tube)

• Controls pressure within the middle ear Middle ear The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. Acute Otitis Media and on both sides of the tympanic membrane
• Located anterior to the tympanic cavity
• Connects the middle ear Middle ear The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. Acute Otitis Media to the nasopharynx Nasopharynx The top portion of the pharynx situated posterior to the nose and superior to the soft palate. The nasopharynx is the posterior extension of the nasal cavities and has a respiratory function. Pharynx: Anatomy

Inner Ear

The inner ear is located within the petrous part of the temporal bone Temporal bone Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull). Jaw and Temporomandibular Joint: Anatomy and contains the organs of hearing and equilibrium Equilibrium Occurs when tumor cells survive the initial elimination attempt These cells are not able to progress, being maintained in a state of dormancy by the adaptive immune system. In this phase, tumor immunogenicity is edited, where T cells keep selectively attacking highly immunogenic tumor cells.This attack leaves other cells with less immunogenicity to potentially develop resistance to the immune response. Cancer Immunotherapy.

Bony labyrinth

The bony labyrinth is filled with perilymph and is separated from the middle ear Middle ear The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. Acute Otitis Media by the medial wall of the tympanic cavity.

• Vestibule: central bony cavity:
  • Contains the utricle Utricle A membranous sac within the vestibular labyrinth of the inner ear. The utricle communicates with the saccule through the utriculosaccular duct from which the endolymphatic duct arises. The utricle and saccule have sensory areas (acoustic maculae) which are innervated by the vestibular nerve. Auditory and Vestibular Pathways: Anatomy and saccule Saccule A membranous sac within the vestibular labyrinth of the inner ear. The saccule communicates with cochlear duct through the ductus reuniens, and communicates with utricle through the utriculosaccular duct from which the endolymphatic duct arises. The utricle and saccule have sensory areas (acoustic maculae) which are innervated by the vestibular nerve. Auditory and Vestibular Pathways: Anatomy 
  • Communicates with the middle ear Middle ear The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. Acute Otitis Media in 3 directions:
    • Laterally through the oval window
    • Anteriorly with the cochlea
    • Posteriorly with the semicircular canals Semicircular canals Three long canals (anterior, posterior, and lateral) of the bony labyrinth. They are set at right angles to each other and are situated posterosuperior to the vestibule of the bony labyrinth (vestibular labyrinth). The semicircular canals have five openings into the vestibule with one shared by the anterior and the posterior canals. Within the canals are the semicircular ducts. Auditory and Vestibular Pathways: Anatomy 
• Semicircular canals Semicircular canals Three long canals (anterior, posterior, and lateral) of the bony labyrinth. They are set at right angles to each other and are situated posterosuperior to the vestibule of the bony labyrinth (vestibular labyrinth). The semicircular canals have five openings into the vestibule with one shared by the anterior and the posterior canals. Within the canals are the semicircular ducts. Auditory and Vestibular Pathways: Anatomy: 3 canals at 90-degree angles to each other:
  • Anterior canal = sagittal Sagittal Computed Tomography (CT) plane
  • Posterior canal = frontal Frontal The bone that forms the frontal aspect of the skull. Its flat part forms the forehead, articulating inferiorly with the nasal bone and the cheek bone on each side of the face. Skull: Anatomy plane
  • Lateral canal = transverse plane Transverse plane Anterior Abdominal Wall: Anatomy
• Cochlea: spiral-shaped bony cavity:
  • Spiral Spiral Computed tomography where there is continuous x-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures. Computed Tomography (CT) lamina: superior scala vestibuli and inferior scala tympani
  • Central bony column = modiolus

Membranous labyrinth

The membranous labyrinth is filled with endolymph Endolymph The lymph fluid found in the membranous labyrinth of the ear. Vertigo and is composed of the vestibular and cochlear labyrinths.

• Vestibular labyrinth: 
  • Comprised of the utricle Utricle A membranous sac within the vestibular labyrinth of the inner ear. The utricle communicates with the saccule through the utriculosaccular duct from which the endolymphatic duct arises. The utricle and saccule have sensory areas (acoustic maculae) which are innervated by the vestibular nerve. Auditory and Vestibular Pathways: Anatomy, saccule Saccule A membranous sac within the vestibular labyrinth of the inner ear. The saccule communicates with cochlear duct through the ductus reuniens, and communicates with utricle through the utriculosaccular duct from which the endolymphatic duct arises. The utricle and saccule have sensory areas (acoustic maculae) which are innervated by the vestibular nerve. Auditory and Vestibular Pathways: Anatomy, and 3 membranous semicircular ducts
  • Contains sensory Sensory Neurons which conduct nerve impulses to the central nervous system. Nervous System: Histology organs for balance
• Cochlear labyrinth:
  • Sensory Sensory Neurons which conduct nerve impulses to the central nervous system. Nervous System: Histology organ for hearing
  • Scala vestibuli:
    • Contains perilymph
    • Anterior chamber Anterior chamber The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. Eye: Anatomy up which sound travels
  • Scala tympani:
    • Contains perilymph
    • Posterior chamber Posterior chamber Eye: Anatomy down which sound travels
  • Scala media (cochlear duct):
    • Contains endolymph Endolymph The lymph fluid found in the membranous labyrinth of the ear. Vertigo
    • Located between scala vestibuli and scala tympani
    • Houses organ of Corti Organ of Corti The spiral epithelium containing sensory auditory hair cells and supporting cells in the cochlea. Organ of corti, situated on the basilar membrane and overlaid by a gelatinous tectorial membrane, converts sound-induced mechanical waves to neural impulses to the brain. Auditory and Vestibular Pathways: Anatomy
• Organ of Corti Organ of Corti The spiral epithelium containing sensory auditory hair cells and supporting cells in the cochlea. Organ of corti, situated on the basilar membrane and overlaid by a gelatinous tectorial membrane, converts sound-induced mechanical waves to neural impulses to the brain. Auditory and Vestibular Pathways: Anatomy:
  • Spiral Spiral Computed tomography where there is continuous x-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures. Computed Tomography (CT) organ within cochlear labyrinth
  • Contains mechanoreceptors called hair cells Hair cells Auditory sensory cells of organ of corti, usually placed in one row medially to the core of spongy bone (the modiolus). Inner hair cells are in fewer numbers than the outer auditory hair cells, and their stereocilia are approximately twice as thick as those of the outer hair cells. Auditory and Vestibular Pathways: Anatomy
  • Hair cells Hair cells Auditory sensory cells of organ of corti, usually placed in one row medially to the core of spongy bone (the modiolus). Inner hair cells are in fewer numbers than the outer auditory hair cells, and their stereocilia are approximately twice as thick as those of the outer hair cells. Auditory and Vestibular Pathways: Anatomy determine the movement and position of the head in space.
  • Types I (bulbous) and II (elongated) hair cells Hair cells Auditory sensory cells of organ of corti, usually placed in one row medially to the core of spongy bone (the modiolus). Inner hair cells are in fewer numbers than the outer auditory hair cells, and their stereocilia are approximately twice as thick as those of the outer hair cells. Auditory and Vestibular Pathways: Anatomy
    • Both types have stereocilia of varying lengths at the apex. 
    • Stereocilia respond to movement of endolymph Endolymph The lymph fluid found in the membranous labyrinth of the ear. Vertigo. 
    • Kinocilium: single cilium at lateral portion of hair cell, defines polarity of the cell
    • Hair cells Hair cells Auditory sensory cells of organ of corti, usually placed in one row medially to the core of spongy bone (the modiolus). Inner hair cells are in fewer numbers than the outer auditory hair cells, and their stereocilia are approximately twice as thick as those of the outer hair cells. Auditory and Vestibular Pathways: Anatomy in the organ of Corti Organ of Corti The spiral epithelium containing sensory auditory hair cells and supporting cells in the cochlea. Organ of corti, situated on the basilar membrane and overlaid by a gelatinous tectorial membrane, converts sound-induced mechanical waves to neural impulses to the brain. Auditory and Vestibular Pathways: Anatomy lack kinocilium.

Neurovasculature of the Ear

Clinical Relevance

• Otitis externa Otitis externa Otitis externa (also known as external otitis or swimmer’s ear) is an infection of the external auditory canal that is most often caused by acute bacterial infection and is frequently associated with hot, humid weather and water exposure. Patients commonly present with ear pain, pruritus, discharge, and hearing loss. Otitis Externa: inflammation Inflammation Inflammation is a complex set of responses to infection and injury involving leukocytes as the principal cellular mediators in the body’s defense against pathogenic organisms. Inflammation is also seen as a response to tissue injury in the process of wound healing. The 5 cardinal signs of inflammation are pain, heat, redness, swelling, and loss of function. Inflammation of the external acoustic meatus. Otitis externa Otitis externa Otitis externa (also known as external otitis or swimmer’s ear) is an infection of the external auditory canal that is most often caused by acute bacterial infection and is frequently associated with hot, humid weather and water exposure. Patients commonly present with ear pain, pruritus, discharge, and hearing loss. Otitis Externa is a bacterial infection that most commonly occurs in children. The typical causative organisms are Pseudomonas Pseudomonas Pseudomonas is a non-lactose-fermenting, gram-negative bacillus that produces pyocyanin, which gives it a characteristic blue-green color. Pseudomonas is found ubiquitously in the environment, as well as in moist reservoirs, such as hospital sinks and respiratory equipment. Pseudomonas and Staphylococcus Staphylococcus Staphylococcus is a medically important genera of Gram-positive, aerobic cocci. These bacteria form clusters resembling grapes on culture plates. Staphylococci are ubiquitous for humans, and many strains compose the normal skin flora. Staphylococcus aureus. Presentation is with exquisite tenderness on manipulation of the external ear. Treatment is with antibiotic eardrops.
• Acute otitis media Acute Otitis Media Acute otitis media is an infection in the middle ear characterized by mucosal inflammation and retention of fluid. The most common pathogens are Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. The condition can present with fever, otalgia, and diminished hearing. Acute Otitis Media: acute inflammation Inflammation Inflammation is a complex set of responses to infection and injury involving leukocytes as the principal cellular mediators in the body’s defense against pathogenic organisms. Inflammation is also seen as a response to tissue injury in the process of wound healing. The 5 cardinal signs of inflammation are pain, heat, redness, swelling, and loss of function. Inflammation of the middle ear Middle ear The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. Acute Otitis Media due to viral or bacterial infections Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases. Chronic Granulomatous Disease. The condition is most common in children ages 6–18 months. Presentation is with fever Fever Fever is defined as a measured body temperature of at least 38°C (100.4°F). Fever is caused by circulating endogenous and/or exogenous pyrogens that increase levels of prostaglandin E2 in the hypothalamus. Fever is commonly associated with chills, rigors, sweating, and flushing of the skin. Fever, symptoms of upper respiratory tract infection, and ear pain Pain An unpleasant sensation induced by noxious stimuli which are detected by nerve endings of nociceptive neurons. Pain: Types and Pathways. The majority of cases are caused by viruses Viruses Minute infectious agents whose genomes are composed of DNA or RNA, but not both. They are characterized by a lack of independent metabolism and the inability to replicate outside living host cells. Virology, but antibiotics should be initiated if a bacterial etiology is suspected.
• Vertigo Vertigo Vertigo is defined as the perceived sensation of rotational motion while remaining still. A very common complaint in primary care and the ER, vertigo is more frequently experienced by women and its prevalence increases with age. Vertigo is classified into peripheral or central based on its etiology. Vertigo: sensation of movement between oneself and surroundings. Vertigo Vertigo Vertigo is defined as the perceived sensation of rotational motion while remaining still. A very common complaint in primary care and the ER, vertigo is more frequently experienced by women and its prevalence increases with age. Vertigo is classified into peripheral or central based on its etiology. Vertigo is not limited to a feeling of rotation Rotation Motion of an object in which either one or more points on a line are fixed. It is also the motion of a particle about a fixed point. X-rays but may include other forms of movement, such as upward lifting, swaying, rocking, or nonsystematic movement. It is usually a symptom of an underlying condition such as labyrinthitis, Ménière disease Ménière disease Ménière disease is a condition characterized by episodes of vertigo, tinnitus, and hearing loss, likely caused by endolymphatic hydrops of the labyrinthine system in the inner ear. The risk factors include a family history of Ménière disease, preexisting autoimmune disorders, allergies, and trauma to the head or ear. Ménière Disease, or an adverse reaction to medications.
• Ménière disease Ménière disease Ménière disease is a condition characterized by episodes of vertigo, tinnitus, and hearing loss, likely caused by endolymphatic hydrops of the labyrinthine system in the inner ear. The risk factors include a family history of Ménière disease, preexisting autoimmune disorders, allergies, and trauma to the head or ear. Ménière Disease: characterized by a symptom triad of vertigo Vertigo Vertigo is defined as the perceived sensation of rotational motion while remaining still. A very common complaint in primary care and the ER, vertigo is more frequently experienced by women and its prevalence increases with age. Vertigo is classified into peripheral or central based on its etiology. Vertigo, tinnitus Tinnitus A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of cochlear diseases; vestibulocochlear nerve diseases; intracranial hypertension; craniocerebral trauma; and other conditions. Cranial Nerve Palsies, and hearing impairment Hearing impairment Hearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss. The episodes of vertigo Vertigo Vertigo is defined as the perceived sensation of rotational motion while remaining still. A very common complaint in primary care and the ER, vertigo is more frequently experienced by women and its prevalence increases with age. Vertigo is classified into peripheral or central based on its etiology. Vertigo in Ménière disease Ménière disease Ménière disease is a condition characterized by episodes of vertigo, tinnitus, and hearing loss, likely caused by endolymphatic hydrops of the labyrinthine system in the inner ear. The risk factors include a family history of Ménière disease, preexisting autoimmune disorders, allergies, and trauma to the head or ear. Ménière Disease can last from a few minutes to several hours, and the hearing impairment Hearing impairment Hearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss mostly affects low frequencies. Treatment is geared toward nausea Nausea An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses. Antiemetics prevention and physical therapy Physical Therapy Becker Muscular Dystrophy to maintain physical functionality.
• Hearing loss Hearing loss Hearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss: hearing impairments are classified into conductive hearing loss Hearing loss Hearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss and sensorineural hearing loss Hearing loss Hearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss. Conductive hearing loss Hearing loss Hearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss stems from damage to the middle ear Middle ear The space and structures directly internal to the tympanic membrane and external to the inner ear (labyrinth). Its major components include the auditory ossicles and the eustachian tube that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. Acute Otitis Media, which prevents the proper transmission of sound. In sensorineural hearing loss Hearing loss Hearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss, the hearing organ is damaged.
• Tinnitus Tinnitus A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of cochlear diseases; vestibulocochlear nerve diseases; intracranial hypertension; craniocerebral trauma; and other conditions. Cranial Nerve Palsies: perception Perception The process by which the nature and meaning of sensory stimuli are recognized and interpreted. Psychiatric Assessment of noise or “ringing in the ears.” Tinnitus Tinnitus A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of cochlear diseases; vestibulocochlear nerve diseases; intracranial hypertension; craniocerebral trauma; and other conditions. Cranial Nerve Palsies is a common condition that is experienced in the absence of an external auditory stimulus. The sound perceived is described as whistling, hissing, buzzing, ringing, and/or pulsating. Tinnitus Tinnitus A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of cochlear diseases; vestibulocochlear nerve diseases; intracranial hypertension; craniocerebral trauma; and other conditions. Cranial Nerve Palsies may be related to underlying conditions such as Ménière disease Ménière disease Ménière disease is a condition characterized by episodes of vertigo, tinnitus, and hearing loss, likely caused by endolymphatic hydrops of the labyrinthine system in the inner ear. The risk factors include a family history of Ménière disease, preexisting autoimmune disorders, allergies, and trauma to the head or ear. Ménière Disease, ear and sinus infections Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases. Chronic Granulomatous Disease, and brain Brain The part of central nervous system that is contained within the skull (cranium). Arising from the neural tube, the embryonic brain is comprised of three major parts including prosencephalon (the forebrain); mesencephalon (the midbrain); and rhombencephalon (the hindbrain). The developed brain consists of cerebrum; cerebellum; and other structures in the brain stem. Nervous System: Anatomy, Structure, and Classification tumors.