Postinfectious glomerulonephritis (GN) is a type of nephritis classically caused by a prior infection with group A beta-hemolytic Streptococcus , which is referred to as poststreptococcal glomerulonephritis (PSGN). The clinical presentation of PSGN can range from asymptomatic, microscopic hematuria to full-blown acute nephritic syndrome, which is characterized by red-to-brown urine, proteinuria, edema, and acute kidney injury. The diagnosis is made based on clinical findings in the setting of recent group A Streptococcus (GAS) infection. Management is supportive and involves treating the clinical manifestations. The prognosis is generally favorable (especially in children), typically with spontaneous resolution.
Last updated: 29 Apr, 2022
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