Bronchogenic carcinoma, simply called lung cancer, is a malignant tumor arising from the epithelial lining of the bronchus or bronchiole.
Epidemiology and Etiology
The incidence of bronchogenic carcinoma is estimated to be more than 200,000 cases per year making it the second most common malignancy in the United States, after prostate cancer in men and breast cancer in women. Mortality-wise, it causes the highest cancer-related deaths in the United States, about 160,000 deaths per year in the United States are related to bronchogenic carcinoma. The average age at the time of diagnosis is around 65 years.
Tobacco smoking is the single most important etiologic risk factor for the bronchogenic carcinoma. The risk of bronchogenic carcinoma has a direct relationship with the duration and dose of tobacco smoking. The passive (second-hand) smoking is also a risk factor.
The other known risk factors for bronchogenic carcinoma are exposure to asbestos, radon, arsenic, beryllium, chromium, nickel and soot.