Subcutaneous, Cutaneous, and Superficial Mycoses

by Vincent Racaniello, PhD

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    Hello and welcome to Subcutaneous, Cutaneous and Superficial Mycoses. This is the last in our discussion of various fungal diseases. And after you hear this lecture, you will be able to name some fungi that cause cutaneous, subcutaneous, and superficial mycoses. You will be familiar with the pathogenesis and epidemiology of sporotrichosis, tinea, seborrheic dermatitis, and tinea versicolor. And you'll know which drugs can be used to treat cutaneous, subcutaneous and superficial mycoses. The first we will talk about is Sporotrichosis, and this is an infection caused by Sporothrix schenckii, which like many of the fungi we've been discussing, is a dimorphic fungus. It can alternate between filamentous forms which you can see on the right and yeast or single cell forms on the left. Come to think of it, can you name one of the fungi that we've talked about which is not dimorphic? I’ll give you a few seconds. If you said Saccharomyces cerevisiae, you’d be right. Sporothrix schenckii, this is a mold in the environment. It’s an environmental fungus, it grows, is hyphae and mycelia, this produces spores of course, to produce more organisms in the wild and it is the spores that are infectious. Interestingly for the Sporotrichosis organism, it is temperature that causes the change in the body form. So at high temperatures, the temperature of the human body, 37 Celsius or 98 Fahrenheit, this causes the fungus to assume the yeast form. Normally in the environment it prefers to grow at lower temperatures at which it grows in the mycelia forms. This fungus is present in soil, it's present in moss, decaying wood, vegetation, throughout the world.It's everywhere. It's ubiquitous as we say, and it's an environmental fungus, very much like the other ones that we've talked about. Acquisition of the disease, Sporotrichosis, is...

    About the Lecture

    The lecture Subcutaneous, Cutaneous, and Superficial Mycoses by Vincent Racaniello, PhD is from the course Fungi. It contains the following chapters:

    • Subcutaneous, Cutaneous and Superficial Mycoses
    • Sporotrichosis
    • Dermatophytes
    • Malassezia
    • Fungal Mycoses: Learning Outcomes

    Included Quiz Questions

    1. Tinea onychomycosis: finger or toe nails.
    2. Tinea capitis: crotch.
    3. Tinea pedis: head.
    4. Tinea cruris: feet.
    5. Tinea ungiuim: hands.
    1. Most commonly, people can inhale the spores and this causes pulmonary sporotrichosis.
    2. It is a dimorphic fungus which can alternate between filamentous forms.
    3. The infection is spread by introducing spores into the body.
    4. This fungus is present in soil, it's present in moss, decaying wood, vegetation, etc. and acquisition of the disease is mostly associated with people who work outdoors or with people who have jobs involving farming, landscaping, and gardening.
    5. Sporotrichosis can be treated with Itraconazole.
    1. In aerosolized particles in the air.
    2. In soil.
    3. In animals.
    4. On locker room floors.
    5. On shower walls.
    1. Through a break in the skin.
    2. From eating contaminated food.
    3. Via the fecal-oral route.
    4. Being diffused through pores on the skin.
    5. Through contaminated drinking water.
    1. Athlete's Foot.
    2. Seborrheic dermatitis.
    3. Pruritic erythematous patches in the eyebrows, mustache or beard.
    4. Tinea versicolor.
    5. Dandruff.
    1. Itraconazole, topical.
    2. Terbinafine, topical.
    3. Ketoconazole, oral.
    4. Itraconazole, IV.
    5. Terbinafine, oral.

    Author of lecture Subcutaneous, Cutaneous, and Superficial Mycoses

     Vincent Racaniello, PhD

    Vincent Racaniello, PhD

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