Parasites: Plasmodium

by Vincent Racaniello, PhD

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    Hello and welcome to Parasites: Plasmodium. We’re going to be going a bit deeper into diseases caused by several individual types of parasites. And after you've watched this lecture, you will know that the four different strains of human malaria parasites are transmitted by mosquitoes. You will be familiar with the Plasmodium lifecycle, both in the mosquito and in humans, and you’ll understand how to prevent and treat malaria. Just to remind you, protozoa are single celled eukaryotes and we’re going to be talking about protozoan parasites in the next few lectures, and these include the Plasmodium species, the causative agents of malaria. There are a variety of different Plasmodium that cause human malaria, Plasmodium falciparum for example and this blood smear stained to visualize two parasite containing red blood cells, the pictures are slightly different for each organism. Plasmodium vivax is another malaria causing protozoan parasite. Plasmodium malariae and finally Plasmodium ovale, the diseases caused by these different Plasmodium species have overall features in similar fashion, but they do have some differences and there are slight geographic differences as to the location of the parasites. This global map shows you the regions of the world in which infection with the Plasmodia species occur. The malarias, you can see most of Africa is affected in red, a good part of Asia, Central and South America. So the regions, essentially border the equator, these are where the mosquitoes are found that transmit the infection. The malarias are responsible for 2 billion infections every year, just think of that in the context of the population of earth. This is huge and 3 million deaths mostly in Africa and mostly in children less than five years of age. And this is the real tragedy of malaria that it targets children and makes them...

    About the Lecture

    The lecture Parasites: Plasmodium by Vincent Racaniello, PhD is from the course Parasites. It contains the following chapters:

    • Parasites: Plasmodium
    • Protozoa
    • The Malarias
    • Plasmodium Falciparum Life Cycle
    • Malaria Clinical Signs and Symptoms
    • Malaria Diagnosis
    • Malaria Treatment
    • Malaria Prevention
    • Plasmodium: Learning Outcomes

    Included Quiz Questions

    1. Plasmodium sporozyte.
    2. Plasmodium falciparum.
    3. Pladmodium vivax.
    4. Plasmodium malariae.
    5. Plasmodium ovale.
    1. Chloroquinine.
    2. Mefloquine.
    3. Malarone.
    4. Quinine.
    5. Halofantrine.
    1. An anti-malarial vaccine.
    2. Wearing insect repellent on the body during the day.
    3. Having a mosquito net over the bed at night.
    4. Covering the body with clothing.
    5. Putting screens in windows.
    1. It is transmitted among humans by the bite of an infected female anopheline mosquito.
    2. There are animal variants of these malarias and then can cause human disease.
    3. There are three different strains of human malaria parasites.
    4. The use of the artemisin drug type over many years led to extensive resistance, so it is no longer useful.
    5. A window screen does not cut down on likelihood of contracting malaria.

    Author of lecture Parasites: Plasmodium

     Vincent Racaniello, PhD

    Vincent Racaniello, PhD

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