Parasites: Leishmania

by Vincent Racaniello, PhD

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    Hello and welcome to Leishmania. This is one of a series of lectures where we'll look in depth at individual human parasites. After you hear this lecture, you will understand the lifecycle of leishmania and how it's transmitted to humans. You'll be familiar with the pathogenesis of the different forms of leishmaniasis and you'll understand how to prevent and treat leishmaniasis. We've been looking at a series of protozoan parasites and just to remind you, these are single celled eukaryotes of medical importance. We've looked at plasmodium, toxoplasma and now let's take a look at the leishmania. Here is a photograph of the blood form of leishmania, these are flagellated protozoan parasites, and leishmania come in a variety of species which are medically important. These species have different disease outcomes and have different global distributions. On the left, you have the distribution of a disease we call cutaneous leishmaniasis. This is a disease as you will see that mainly affects the skin and on the right is visceral leishmaniasis, where the parasite causes disease in your internal organs. Now you can see by just a glance at these two maps, that the distributions are overlapping but not identical. If we look at cutaneous first on the left, the darker countries have more cases, so you can see Central and South America have a number of cases, Africa, the north western part of the country and Egypt, Central Asia and that's cutaneous. Now on the right, if you look at visceral leishmaniasis, you see Central and South America as well, but now a different distribution on the eastern part of Africa and particularly high levels of cases in India. And these are reflection of in part that the animals that are infected and the vectors that transmit them. Now one of...

    About the Lecture

    The lecture Parasites: Leishmania by Vincent Racaniello, PhD is from the course Microbiology: Advanced. It contains the following chapters:

    • Parasites: Leishmania
    • Leishmaniasis
    • Leishmania Tropica
    • Leishmania brazilliensis
    • Leishmania donovani
    • Leishmaniasis - Diagnosis
    • Leishmaniasis - Treatment and Prevention
    • Leishmania: Learning Outcomes

    Author of lecture Parasites: Leishmania

     Vincent Racaniello, PhD

    Vincent Racaniello, PhD

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