Introduction to Fungi

by Vincent Racaniello, PhD

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    Hello and welcome to Fungi. We're going to delve into this topic in a little more detail and I want to start with some general principles. And after this lecture, I hope that you'll be able to distinguish the two general types of fungi. You should know the different types of human fungal diseases and their origins, and you should be familiar with the drugs that are used to treat fungal infections. There are two kinds of fungi morphologically. Most of the fungi that we know of, are called filamentous fungi, and these are diagrammed here. They can be made up of very extensive networks of filaments. These are composed of hyphae and mycelia. So mycelium is the name for the entire filamentous growth and it's made up of smaller segments called hyphae. So these constitute most of the fungi that we know of in nature. These reproduce by dividing. They also produce spores, you can see a structure on this mycelium that produces spores and of course the spores disperse in nature on animals and in the wind and they seed new growth, so the fungi elsewhere. So these are filamentous fungi. Mushrooms are fungi. They are produced by filamentous fungi. The filamentous part of the mycelium of course grows on or in the ground, you don't see it very easily. It’s microscopic. But periodically the mycelia are simply rearranged and grouped together to form a mushroom. The mushroom comes out of the ground and its sole purpose is to produce spores, which drop out of the cap of the mushroom, they drop on the ground, they are dispersed and they initiate the growth of a new fungus. Now I say the sole purpose is to make spores, but of course humans like to eat mushrooms, some of them...

    About the Lecture

    The lecture Introduction to Fungi by Vincent Racaniello, PhD is from the course Fungi. It contains the following chapters:

    • Eukaryotic Microbes - Fungi
    • Fungal Dimorphism
    • Fungal Infections
    • Sources of Fungal Infections
    • Antifungal Agents
    • Eukaryotic Microbes - Fungi: Learning Outcomes

    Included Quiz Questions

    1. Fungi are all strict anaerobes.
    2. There are two major types of fungi- filamentous and yeasts.
    3. Fungi CANNOT make their own precursors.
    4. Fungi can secrete enzymes that can digest cellulose from plants.
    5. Fungi are heterotrophs.
    1. In an environment lacking oxygen.
    2. In the grout between bathtub tiles.
    3. In a vat of fresh beer bring brewed.
    4. On a rotting tree trunk.
    5. On a piece of fruit abandoned in a school locker.
    1. ...they can grow with one of two forms.
    2. ...they can only reproduce asexually.
    3. ...they can only grow inside a place that is dark.
    4. ...they die once producing offspring.
    5. ...they are made of only two key materials.
    1. An infection that specifically targets previously healthy patients rather than the immunocompromised: Irregular mycoses
    2. An infection that involves the skin or the underlying tissue that can get into the lymphatic system and spread throughout : Subcutaneous mycoses
    3. Infections limited to the surface of the skin and the skin structures : Superficial / Cutaneous mycoses
    4. Infections caused by geographically restricted fungi, that is, they only occur in certain places in the world : Endemic mycoses
    5. Infections specifically in immunosuppressed patients : Opportunistic mycoses
    1. Nystatin inhibits DNA and protein synthesis.
    2. The polyenes and allylamines bind a component of the cell membrane called ergosterol, which disrupts the membrane.
    3. Nystatin is a commonly used topical antifungal that is used to treat many different types of surface infections.
    4. The echinocandins inhibit cell wall synthesis.
    5. The azoles are used to block the synthesis of ergosterol.
    1. Ketoconazole
    2. Itraconazole
    3. Fluconazole
    4. Voriconazole
    5. Caspofungin

    Author of lecture Introduction to Fungi

     Vincent Racaniello, PhD

    Vincent Racaniello, PhD

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    clear well explained in simple terms in bite size pieces
    By Christopher M. on 30. January 2017 for Introduction to Fungi

    clear well explained in simple terms in bite size pieces