Cystic fibrosis is an autosomal recessive disease that affects the respiratory system, pancreas, hepatobiliary tract, sinuses and intestine. Abnormal transport of chloride, sodium and bicarbonate across the cell membrane is the mainstay of pathology leading to tenacious viscous body secretions. Patients present with pulmonary infections, sinusitis, pancreatitis, infetility and intestinal obstruction.
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