Cellular Injury
Cellular Injury

Cellular Injury

by Richard Mitchell, MD, PhD

Cellular injury describes the stress-induced changes that a cell undergoes secondary to internal or external insults. There are thousands of ways a cell might be injured, but each of these etiologies culminates in a common cascade of cellular injury, starting with depletion of cellular ATP, followed by cell membrane permeabilization and biochemical pathway disruption, and culminating in irreversible DNA damage. Cell damage can be reversible or irreversible, depending on what step of the process has already occurred. Also, depending on the extent of injury, the cellular response may be adaptive and, where possible, homeostasis is restored. When injury severity exceeds the cell’s self-repair mechanisms, cell death occurs, either by necrosis or apoptosis.

Course Details

  • Videos 27
  • Duration 2:07 h
  • Quiz questions 61
  • Concept Pages 3


Your Educators of course Cellular Injury

 Richard Mitchell, MD, PhD

Richard Mitchell, MD, PhD

Dr. Richard N. Mitchell is the Lawrence J. Henderson Professor of Pathology and Health Sciences and Technology, at Harvard Medical School in Massachusetts, USA.

He obtained his PhD in Cell Biology and Immunology from Rockefeller University in 1980, and his MD from Harvard Medical School in 1984. Currently, he is Program Director of the Health Sciences and Technology Education and Curriculum at Harvard Medical School.

Due to his achievements, he earned the ASIP Robbins Distinguished Educator Award in 2013.

Within Lecturio, Dr. Mitchell teaches courses on Pathology.

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Cellular injury videos
By Nikki . on 02. June 2024 for Cellular Injury

i will recommend all levels of students to use lecturio as a resource tool.

I really liked it; I loved the teaching method and the way he explains.
By Sara D. on 25. May 2024 for Chemical Agents – Etiologies of Cellular Injury

I really liked it; I loved the teaching method and the way he explains.

he is implacable
By birehan e. on 04. April 2024 for Hypoxia – Etiologies of Cellular Injury

he is very great. he is very explanatory. he takes his time when explaining things

Very professional and clear.
By Tomas9A11 . on 21. February 2024 for Necrosis: Cellular Homicide

Great clarity, illustrations, and attention to detail. Thank you very much!