Cellular Injury
Cellular Injury

Cellular Injury

by Richard Mitchell, MD

Cellular injury describes the stress-induced changes that a cell undergoes secondary to internal or external insults. There are thousands of ways a cell might be injured, but each of these etiologies culminates in a common cascade of cellular injury, starting with depletion of cellular ATP, followed by cell membrane permeabilization and biochemical pathway disruption, and culminating in irreversible DNA damage. Cell damage can be reversible or irreversible, depending on what step of the process has already occurred. Also, depending on the extent of injury, the cellular response may be adaptive and, where possible, homeostasis is restored. When injury severity exceeds the cellโ€™s self-repair mechanisms, cell death occurs, either by necrosis or apoptosis.

Course Details

  • Videos 27
  • Duration 2:07 h
  • Quiz questions 66
  • Concept Pages 3


Your Educators of course Cellular Injury

 Richard Mitchell, MD

Richard Mitchell, MD

Dr. Richard N. Mitchell is the Lawrence J. Henderson Professor of Pathology and Health Sciences and Technology, at Harvard Medical School in Massachusetts, USA.

He obtained his PhD in Cell Biology and Immunology from Rockefeller University in 1980, and his MD from Harvard Medical School in 1984. Currently, he is Program Director of the Health Sciences and Technology Education and Curriculum at Harvard Medical School.

Due to his achievements, he earned the ASIP Robbins Distinguished Educator Award in 2013.

Within Lecturio, Dr. Mitchell teaches courses on Pathology.

User reviews

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too good, best pathology professor!
By HEER P. on 27. April 2023 for Function vs. Morphology of Cellular Injury

too good, best pathology professor! He explains the concepts in very precise way and gives the right information.

By Jane I. on 02. July 2022 for Cellular Injury

???? He teaches well and itโ€™s over all good. I like it

By Aerianna H. on 31. January 2022 for Cellular Injury

VERY easy to follow along with and understand. Definitely helping me pass patho

Lovely job
By Meritxell S. on 23. September 2021 for Reversible Cellular Injury

Very well explained, interesting. I really like this teacher and series.