Cellular Injury
Cellular Injury

Cellular Injury

by Richard Mitchell, MD, PhD

Cellular injury describes the stress-induced changes that a cell undergoes secondary to internal or external insults. There are thousands of ways a cell might be injured, but each of these etiologies culminates in a common cascade of cellular injury, starting with depletion of cellular ATP, followed by cell membrane permeabilization and biochemical pathway disruption, and culminating in irreversible DNA damage. Cell damage can be reversible or irreversible, depending on what step of the process has already occurred. Also, depending on the extent of injury, the cellular response may be adaptive and, where possible, homeostasis is restored. When injury severity exceeds the cell’s self-repair mechanisms, cell death occurs, either by necrosis or apoptosis.

Course Details

  • Videos 27
  • Duration 2:07 h
  • Quiz questions 65
  • Concept Pages 3


Your Educators of course Cellular Injury

 Richard Mitchell, MD, PhD

Richard Mitchell, MD, PhD

Dr. Richard N. Mitchell is the Lawrence J. Henderson Professor of Pathology and Health Sciences and Technology, at Harvard Medical School in Massachusetts, USA.

He obtained his PhD in Cell Biology and Immunology from Rockefeller University in 1980, and his MD from Harvard Medical School in 1984. Currently, he is Program Director of the Health Sciences and Technology Education and Curriculum at Harvard Medical School.

Due to his achievements, he earned the ASIP Robbins Distinguished Educator Award in 2013.

Within Lecturio, Dr. Mitchell teaches courses on Pathology.

User reviews

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Very professional and clear.
By Tomas9A11 . on 21. February 2024 for Necrosis: Cellular Homicide

Great clarity, illustrations, and attention to detail. Thank you very much!

Very easily understandable
By Shikhar Y. on 01. August 2023 for Necrosis vs. Apoptosis

One of the best teachers of Pathology I've ever seen.

too good, best pathology professor!
By HEER P. on 27. April 2023 for Function vs. Morphology of Cellular Injury

too good, best pathology professor! He explains the concepts in very precise way and gives the right information.

By Jane I. on 02. July 2022 for Cellular Injury

???? He teaches well and it’s over all good. I like it