Tuberculosis is one of the granulomatous infecious diseases caused by mycobacterium tuberculosis.
It is an airborne infection that affects the lungs but can spread to the whole body organs. Chronic inflammation, granuloma formation and fibrosis are the main pathology of tuberculosis.
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The TB lectures can be improved, In particular the approach to dx of a pt with suspected TB and in particular when you would consider tissue biopsy. Also the approach to dx of latent tb isn't clear. E,g performing a chest x-ray in high risk patient populations followed by mantoux testing. No mention of what size reaction is considered positive in different population ie immunosuppressed healthcare workers and the general population. The lecture discusses the treatment of active tb but no discussion of treating latent TB. No mention of when you would treat contacts of the index case. Finally serious side effects of TB treatment were not adequately covered. Isoniazid (need for B6 to decrease risk of peripheral neuropathy and megaloblastic anaemia) rifampicin and liver toxicity and drug interactions, ethambutol and occular toxicities and need for monitoring of visual fields and pyrazinamide (hepatoxicity).