Multiple sclerosis (MS) is an autoimmune disease affecting the brain and/or spinal cord. It is characterized by chronic inflammation, demyelination, gliosis, and neuronal loss. Lesions in the CNS are said to be disseminated in time and space, meaning they classically occur at varied spatial and temporal intervals. The clinical course of the disease is quite variable, ranging from stable chronic disease to a rapidly evolving and debilitating illness. The differential diagnosis of MS should also be considered, as there are other rare presentations that may mimic this disease. Fortunately, there have been many advances in treatment. Early diagnosis is important for preventing permanent disability and early death.
Dr. Raj’s lectures have been very helpful to me in understanding complex concepts. Thank you
Dr. Raj nails it, easy and quick, to the point, nothing unnecessary, thank you!!!
this lecture is great, good level of detail and well explained!
Good summary of the topic but would have been also good further discuss some of the immunosuppresive agents and fingolimod. In the dx workup section the use of MRI was also omitted