Obstructive Lung Disease: Emphysema

by Carlo Raj, MD

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    Now that we’ve looked at the overview, of obstructive lung disease and the different overlaps of asthma, chronic bronchitis and emphysema, we dive into the particulars of emphysema. Now, what you must focus upon would be the definition that we are seeing here and the fact that it does technically come under COPD, which if you were to take a look at those overlapping diagnosis of circles that I showed you, then this would be the green shaded area. So, what is emphysema? Defined by abnormal, permanent enlargement of the airspace in distal to the terminal bronchioles. So, where are you? You’re getting closer to your alveoli. You’re thinking about your alveolar ducts and you’re thinking about the alveoli. That is accompanied by destruction of the airspace walls without obvious fibrosis and that’s a big point. Because if fibrosis was to take place then you wouldn’t be referring to obstructive lung disease, would you? No. You would then be referring to restrictive lung disease. Now, before we move on, think about the anatomy of your respiratory tree. Distal to the terminal bronchioles, you are thinking about the respiratory bronchioles, you are thinking about the alveolar duct and alveoli and those structures are supported by parenchyma. There are septae that are involved, keep that in mind, as we go through various steps of emphysema and there will be a little bit of a difference between the damage that’s taking place to the ducts versus the damage that will be taking place permanently to the alveoli. Let us begin. So, to begin with, I want you to take a look at the cartoon and where we are. On the very left, move down the divisions and generations of your trachea through the bronchi, through the bronchiole, eventually through the terminal bronchioles of...

    About the Lecture

    The lecture Obstructive Lung Disease: Emphysema by Carlo Raj, MD is from the course Obstructive Lung Disease. It contains the following chapters:

    • Emphysema
    • Pathogenesis A
    • Pathogenesis B
    • Signs & Symptoms
    • Diagnosis

    Author of lecture Obstructive Lung Disease: Emphysema

     Carlo Raj, MD

    Carlo Raj, MD

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