Kawasaki disease (KD), also known as mucocutaneous lymph node syndrome or infantile polyarteritis, is a medium-sized necrotizing febrile vasculitis that affects children < 5 years of age. Multiple systems are involved but the most serious is the predilection of the coronary arteries. Management involves intravenous immunoglobulin and high-dose aspirin. Follow-up requires serial echocardiograms to monitor for coronary artery aneurysm.