by Stephen Holt, MD, MS

The systemic vasculitides are heterogeneous clinicopathologic disorders that share the common feature of vascular inflammation. The resulting disorder can vary depending on the involvement of specific organs, the caliber of blood vessels, the underlying inflammatory process, and individual host factors. The cumulative result is diminished blood flow, vascular alterations, and eventual occlusion with variable ischemia, necrosis, and tissue damage.

Often, these diseases are considered systemic and tend to involve many organ systems, as blood vessels are ubiquitous in the human body. Therefore, it is extremely important for every physician to be aware of their manifestations. Often, the initial manifestations may be as innocuous as a skin rash but may go on to cause multi-organ compromise. Laboratory testing, imaging, and tissue samples (biopsy) may all be required to make a diagnosis of vasculitis.

Course Details

  • Videos 12
  • Duration 0:48 h
  • Quiz questions 24
  • Concept Pages 7


Your Educators of course Vasculitides

 Stephen Holt, MD, MS

Stephen Holt, MD, MS

Dr. Stephen Holt is the Associate Program Director for Ambulatory Education in the Primary Care Program at the Yale School of Medicine in Connecticut, USA.
He obtained his PhD from Columbia College of Physicians and Surgeons in 2004. Currently, he is Director of the Addiction Recovery Clinic and Codirector of Clinician Educator Distinctions Pathway at Yale School of Medicine.
Because of his achievements, he earned the Faculty Teacher of the Year award from the Yale Primary Care Residency Program in 2009 and 2017.
Within Lecturio, Dr. Holt teaches courses on Physical Examination, Dermatology, and Rheumatology.

User reviews

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By Alaena A. on 28. September 2022 for Eosinophilic Granulomatosis with Polyangiitis: Diagnosis and Management

I like the breakdown and explanation of the case. I especially like the discussion of the management which wasn't covered in other lectures.

This lecture makes you want to learn the topic by virtue of its diction/style alone!
By Ruth W. on 01. September 2022 for Cryoglobulinemic Vasculitis

Rendition diction clear and pleasant. Even if you had no particular interest in this topic, just bumped into it, you may become interested because of its diction/style/clarity being so easy/pleasant to learn/hear.

One of the best
By Malakamir M. on 04. September 2021 for Vasculitides

I am going to watch it it again and again, because I learned a lot from him. He knows how to teach and he used a lot of practical examples to explain his lectures.

Lecture is great
By Irfan A. on 06. April 2021 for Vasculitides

Great,Great,Great,Great,Great, Great,Great,Great,Great,Great,Great