Metabolic Bone Disorders

Metabolic Bone Disorders

by Michael Lazarus, MD

Metabolic bone disorders encompass illnesses that affect the homeostasis of calcium in the body. The concentration of calcium, like that of all other ions, is tightly regulated by multiple mechanisms, enabling adequate storing and absorption in proper time. Inadequate availability or handling of calcium can have deleterious effects in a wide variety of patients (e.g. little children suffering from rickets, middle-aged women undergoing menopause).

In this course, the student will be given a walkthrough of the most common metabolic bone disorders seen in clinical practice, including hypercalcemia, hypocalcemia, hyperparathyroidism, and osteoporosis.

For optimal comprehension, the student is required to have preliminary knowledge of the histology, physiology, and pathology of the parathyroid and the physiology of calcium homeostasis.

Course Details

  • Videos 12
  • Duration 0:48 h
  • Quiz questions 26
  • Concept Pages 14


Your Educators of course Metabolic Bone Disorders

 Michael Lazarus, MD

Michael Lazarus, MD

Dr. Michael Lazarus is a Professor of Clinical Medicine at the David Geffen School of Medicine at the University of California, Los Angeles (UCLA).
He obtained his MD from the University of the Witwatersrand School of Health Sciences, South Africa, and trained at the Washington University School of Medicine. In 2003, he joined the faculty at UCLA and currently serves as the Medical Director of the UCLA Hospitalist Section.
He has won various teaching awards, such as the Serge & Yvette Dadone Clinical Teaching Award, and was featured in the Los Angeles Magazine's Top Doctors Guide in 2021.
Within Lecturio, Dr. Lazarus teaches courses on Endocrinology.

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By S C. on 14. August 2021 for Hypercalcemia: Types and Management

so grateful for such a good lecture on a difficult topic. Very clear summary and helpful hints. Good summary.

By Cerys C. on 25. January 2021 for Hypercalcemia and Review of Calcium Homeostasis

All the important stuff covered without going too in-depth and overcomplicating it.

Very good and didactic lecture. Would expect a little more discussion of pathophysiology
By Ezequiel B. on 27. July 2020 for Paget's Disease with Case

ery good and didactic lecture. Would expect a little more discussion of pathophysiology

Hungry bone syndrome explanation
By Abdul Q. on 01. July 2020 for Iatrogenic Hypoparathyroidism with Case

firstly the reasoning was very vague and not explained well with a quick physiology reference secondly hungry bone syndrome described as surgery for hypoparathyroidectomy . Hungry bone syndrome (HBS) refers to the rapid, profound, and prolonged hypocalcaemia associated with hypophosphataemia and hypomagnesaemia, and is exacerbated by suppressed parathyroid hormone (PTH) levels, which follows parathyroidectomy in patients with severe primary hyperparathyroidism (PHPT) and preoperative high bone turnover.