Metabolic bone disorders encompass illnesses that affect the homeostasis of calcium in the body. The concentration of calcium, like that of all other ions, is tightly regulated by multiple mechanisms, enabling adequate storing and absorption in proper time. Inadequate availability or handling of calcium can have deleterious effects in a wide variety of patients (e.g. little children suffering from rickets, middle-aged women undergoing menopause).
In this course, the student will be given a walkthrough of the most common metabolic bone disorders seen in clinical practice, including hypercalcemia, hypocalcemia, hyperparathyroidism, and osteoporosis.
For optimal comprehension, the student is required to have preliminary knowledge of the histology, physiology, and pathology of the parathyroid and the physiology of calcium homeostasis.
so grateful for such a good lecture on a difficult topic. Very clear summary and helpful hints. Good summary.
All the important stuff covered without going too in-depth and overcomplicating it.
ery good and didactic lecture. Would expect a little more discussion of pathophysiology
firstly the reasoning was very vague and not explained well with a quick physiology reference secondly hungry bone syndrome described as surgery for hypoparathyroidectomy . Hungry bone syndrome (HBS) refers to the rapid, profound, and prolonged hypocalcaemia associated with hypophosphataemia and hypomagnesaemia, and is exacerbated by suppressed parathyroid hormone (PTH) levels, which follows parathyroidectomy in patients with severe primary hyperparathyroidism (PHPT) and preoperative high bone turnover.