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Hemolytic Anemia: Hereditary Spherocytosis (HS) – Red Blood Cell Pathology

by Carlo Raj, MD
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    About the Lecture

    The lecture Hemolytic Anemia: Hereditary Spherocytosis (HS) – Red Blood Cell Pathology by Carlo Raj, MD is from the course Hemolytic Anemia – Red Blood Cell Pathology (RBC). It contains the following chapters:

    • Hereditary Spherocytosis - Etiology
    • Hereditary Spherocytosis - Pathogenesis
    • Hereditary Spherocytosis - Clinical Pathology

    Included Quiz Questions

    1. Spectrin
    2. Globin
    3. Hepcidin
    4. Haptoglobin
    5. Transferrin
    1. Loss of central pallor
    2. None of these
    3. Increased surface area
    4. Biconcave shape
    5. Hypochromic
    1. Autoimmune hemolytic anemia (warm type)
    2. Autoimmune hemolytic anemia (cold type)
    3. Sickle cell anemia
    4. Beta thalassemia
    5. Paroxysmal nocturnal hemoglobinuria
    1. Negative coombs test in spherocytosis
    2. Negative coombs test in autoimmune hemolytic anemia
    3. Negative osmotic fragility test in spherocytosis
    4. Positive osmotic fragility test in autoimmune hemolytic anemia
    5. Positive coombs test in spherocytosis
    1. Osmotic fragility test
    2. Coombs test
    3. Metabisulfate screen
    4. Acidified serum test
    5. Sucrose test
    1. Damage to Na/K ATPase pump in the membrane
    2. Increased surface area of RBC
    3. Damage to Na/Ca pump in the membrane
    4. Damage to Na/Glucose pump in the membrane
    5. Decreased mean hemoglobin concentration
    1. Aplastic crisis
    2. Increased hemolysis
    3. Production of antibodies against RBCs
    4. Increased RBC life span
    5. Decreased hemolysis

    Author of lecture Hemolytic Anemia: Hereditary Spherocytosis (HS) – Red Blood Cell Pathology

     Carlo Raj, MD

    Carlo Raj, MD


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