Influenza A and Tuberculosis

by Jeremy Brown, PhD

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    About the Lecture

    The lecture Influenza A and Tuberculosis by Jeremy Brown, PhD is from the course Infections of the Respiratory Tract. It contains the following chapters:

    • Influenza virus
    • Subacute lung infections
    • Tuberculosis
    • Tuberculosis pathogenesis
    • Clinical manifestations and TB case histories
    • Diagnosis of tuberculosis
    • Treatment of tuberculosis
    • Outcome of TB
    • Summary tuberculosis

    Included Quiz Questions

    1. Influenza is caused by a DNA virus.
    2. Many deaths are caused by exacerbation of chronic disease by influenza infection.
    3. Influenza can cause a severe pneumonia.
    4. All people over 65 years of age should be offered annual influenza vaccination
    1. The histological hallmark of Mycobacterium tuberculosis infection is the presence of caseating granulomas.
    2. Mycobacterium tuberculosis is a rapidly growing bacteria.
    3. Most patients infected with Mycobacterium tuberculosis have active disease.
    4. Mycobacterium tuberculosis is present in environmental water sources.
    1. High socioeconomic status
    2. Recent emigration from a developing country to an industrialised country
    3. Diabetes
    4. Smoking
    1. Massive haemoptysis
    2. Abdominal pain and distension
    3. Reduced conscious level
    4. Painless lump found on one side of the neck
    1. Sputum culture and microscopy
    2. Computed Tomography of the lungs
    3. Chest X ray
    4. Interferon Gamma Release Assay (IGRA) blood test
    1. The shortest recommended period of treatment is 6 months.
    2. Most patients can be treated successfully using only one or two drugs.
    3. Cure is unusual.
    4. Compliance with treatment is often difficult.

    Author of lecture Influenza A and Tuberculosis

     Jeremy Brown, PhD

    Jeremy Brown, PhD

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    TB lectures need improvement
    By Hamed S. on 27. March 2017 for Influenza A and Tuberculosis

    The TB lectures can be improved, In particular the approach to dx of a pt with suspected TB and in particular when you would consider tissue biopsy. Also the approach to dx of latent tb isn't clear. E,g performing a chest x-ray in high risk patient populations followed by mantoux testing. No mention of what size reaction is considered positive in different population ie immunosuppressed healthcare workers and the general population. The lecture discusses the treatment of active tb but no discussion of treating latent TB. No mention of when you would treat contacts of the index case. Finally serious side effects of TB treatment were not adequately covered. Isoniazid (need for B6 to decrease risk of peripheral neuropathy and megaloblastic anaemia) rifampicin and liver toxicity and drug interactions, ethambutol and occular toxicities and need for monitoring of visual fields and pyrazinamide (hepatoxicity).