Gas Transport

by Thad Wilson, PhD

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    In this lecture, we’re dealing with the transport of O2 and CO2. Our learning goals will be to understand O2 transport and be able to differentiate between those modes of transport. Also, you will be to identify the factors that affect oxygen hemoglobin dissociation. Furthermore, after this lecture, you’ll be able to understand CO2 transport and be able to differentiate the modes of transport as well as identify factors that affect that transport. So as we think about O2 transport, we really need to concentrate on what the partial pressure of oxygen is. And so there are three partial pressures that we need to keep in mind. PaO2, PAO2 and PVO2. And the reason why I very much distinguished between capital A and small A O2, is it tells you where to locate it. So PaO2 is the partial pressure of oxygen in the arterial circulation. PAO2 is the partial pressure of oxygen in the alveoli. PVO2 is the partial pressure of oxygen in the venous circulation. And you need to remember what those are as we walk through O2 transport. So to give you an idea of those numbers, the PAO2 is around 95. The PAO2 is around 100, and the PVO2 is around 40 millimeters of mercury. And so those are numbers you want to kind of keep in mind as we walk through this transport of oxygen. Those numbers seem like they are going to be very important because these are the numbers that we measure from an arterial blood gas. So if were to take an arterial sample and measure the amount of oxygen in it, those are the numbers that you get. So this is a very important thing to help us distinguish between if someone has a hypoxemia, versus they have a normal O2...

    About the Lecture

    The lecture Gas Transport by Thad Wilson, PhD is from the course Respiratory Physiology. It contains the following chapters:

    • Oxygen Transport
    • Hemoglobin and O2 Binding
    • Blood Gas Transport Comparison
    • Carbon Dioxide Transport
    • Learning Outcomes

    Included Quiz Questions

    1. 4
    2. 1
    3. 2
    4. 3
    1. Increase in pH
    2. Increase in temperature
    3. Increase in 2,3 DPG
    4. Increase in the partial pressure of carbon dioxide
    1. Oxygen concentration
    2. Partial pressure of oxygen
    3. Partial pressure of carbon dioxide
    4. Bicarbonate concentration
    1. Bicarbonate
    2. Dissolved in the plasma
    3. Carried within red blood cells but not bound to hemoglobin
    4. Bound to hemoglobin

    Author of lecture Gas Transport

     Thad Wilson, PhD

    Thad Wilson, PhD

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