Lectures

Control & Regulation of Breathing

by Thad Wilson, PhD
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    This lecture is about the control and regulation of breathing. We have a number of important learning goals to go through. The first is to identify afferent inputs to the pulmonary system and the respiratory control centers of the brain stem. In this lecture, we will also discuss how the mechanisms by which peripheral and central chemoreceptors sensed changes in the various blood gasses. And finally, we’ll be able to predict the ventilatory response to a given change in our arterial blood gas. Okay. Let’s get started. What are the different parameters that we can control to be able to alter ventilation? We really only have two different things to modulate. The first is going to be breathing frequency or how fast one breaths. The second will be the depth of breath, such as the tidal volume. We have a number of different inputs that will go to the respiratory system. There are three main classifications. We’ll start off with chemoreceptors. They are both central chemoreceptors and peripheral chemoreceptors. There are receptors in the lungs and these will be responsive of the things like lung stretch. And this is very important because if the lungs are overstretched, they’re very fragile environments around the capillaries and the alveoli. And they could stretch too much. There are also irritant receptors in the pulmonary system. There are specialized sensory fibers known as bronchial C fibers as well as juxtacapillary receptors. If we kind of integrate all of the various receptors that we have, let’s start with this. We have central chemoreceptors and they are responsive to hydrogen ions. We start with central chemoreceptors because they are the primary drive for us to breathe. In fact it is kind of interesting that we breathe because we have too much CO2 in the system and...

    About the Lecture

    The lecture Control & Regulation of Breathing by Thad Wilson, PhD is from the course Respiratory Physiology. It contains the following chapters:

    • Control & Regulation of Breathing
    • Engineering Control Systems Approach
    • Central Chemoreceptor
    • Peripheral Chemoreceptors
    • Interrelations of Blood Glasses on Ventilation
    • Other Sensors with Pulmonary Implications
    • Learning Outcomes

    Included Quiz Questions

    1. Dorsal respiratory group neurons
    2. Ventral respiratory group neurons
    3. Apneustic center
    4. Pneumotaxic center
    1. Hydrogen ions
    2. Oxygen
    3. Stretch
    4. Tension
    1. Metabolic acidosis
    2. Sleep
    3. Morphine
    4. Chronic obstructive pulmonary disease
    1. J receptors
    2. Irritant receptors
    3. Stretch receptors
    4. Diaphragm receptors

    Author of lecture Control & Regulation of Breathing

     Thad Wilson, PhD

    Thad Wilson, PhD


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