Inflammatory Vascular Diseases

by Joseph Alpert, MD

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    Vascular medicine, advanced inflammatory diseases. Inflammatory diseases of the blood vessels can be taken care of by cardiologist or vascular medicine specialists but many of them are related to autoimmune diseases and are often taken care of by rheumatologist or immunologist. A number of them occur in children and are taken care of by pediatricians. For the sake of completeness, I am going to cover all of the inflammatory diseases but note it's important to remember that not all of these will come in the average practice of a vascular medicine physician or cardiologist. Well let's start then with the definition. First let's define inflammation. Inflammation is the result of either an infection, for example bacteria or could be a virus, or an injury usually from the immune system or often involving attack by leukocytes who are misinterpreting normal tissue for tissue of an invader. Vasculitis is of course an inflammatory injury in one of the blood vessels. It can occur in the arteries and it can occur in the veins. And in the previous lecture, we have already discussed inflammation in one of these systems, phlebitis. Deep venous thrombosis often starts with inflammatory reaction in the vein wall that then goes on to lead to thrombosis and of course eventually pulmonary embolism. In vasculitis of the arterial system and the venous system, its usually involves first the endothelial cells that become attacked or inflamed and then that is followed by inflammation in the smooth muscle layer or the tunica media of the artery or vein. And as I said before arteries and veins can be affected by the one of a variety of inflammatory conditions. What are the symptoms? The symptoms are often that of systemic disease. Patients may have fever, weight loss. There may be headache, if one...

    About the Lecture

    The lecture Inflammatory Vascular Diseases by Joseph Alpert, MD is from the course Inflammatory Vascular Diseases. It contains the following chapters:

    • Inflammatory diseases - Definition
    • Inflammatory diseases - Classification
    • Polyarteritis nodosa
    • Kawasaki disease
    • Thromboangitis obliterans
    • Inflammatory diseases - Summary

    Included Quiz Questions

    1. The skin is usually not involved
    2. Arteries & veins are affected
    3. Involvement of endothelial cells and smooth muscle layer of the vessel occurs
    4. Vasculitis consists of a group of disorders that causes inflammatory injury and necrosis of vessel wall
    1. By vessel size
    2. By the shape of the vessel
    3. By the quantity of blood flow carried by the vessel
    4. By quality of the vessel endothelium
    1. Small vessel vasculitis
    2. Large vessel vasculitis
    3. Medium sized vessel vasculitis
    4. Adventitial vasculitis
    1. Japan
    2. Germany
    3. Argentina
    4. China
    1. Often associated with rheumatoid arthritis
    2. Heart attack
    3. Stroke
    4. More common in older individuals

    Author of lecture Inflammatory Vascular Diseases

     Joseph Alpert, MD

    Joseph Alpert, MD

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