The generation of energy by breaking down carbohydrates is as old as cells themselves. Carbohydrates are the most important substrate for the synthesis of ATP via glycolysis, so much so that hepatocytes have the ability to synthesize glucose de novo to meet metabolic needs. Furthermore, glucose can be stored in the form of long polymers (glycogen) to make glucose available in the long term.
In this course, the student will be led on a detailed walkthrough of the glycolysis pathway, the steps of gluconeogenesis, and the metabolism of glycogen. Metabolic pathways will be a constant topic of discussion, and the pentose phosphate pathway will be among the most prominent to be discussed. Cellular respiration will also be included in the discussion, touching on the citric acid and glyoxylate cycles.
For optimal comprehension, the student will be required to have familiarity with the basic notions of molecular and cellular biology and the biochemistry of carbohydrates.
I have really learned. Before, I was wondering why study, or cram all those pathways and enzymes. How Professor Kevin Ahern explains and bring out concepts, Oh my God so great. He was born a teacher and just polished by learning! He never leaves behind any one, even the slow learners can pick, because once one understands the basic, the necessary complex facts can be understood quite faster! I am now thinking of mastering in Biochemistry, besides my goal of Internal medicine. To be the best Physician, Biochemistry I have understood is one of the vital tools! In my Nursing practice, we lost a 10 yr old male with Liver Cirrhosis from a liver disease, which was diagnosed in early age. Now, I am thinking of a Deficiency of the Transaldolase enzyme!! Ahh save for my little knowledge! Kind regards!
Really a great and elaborate presentation. Thanks Prof. Kevin. Now I no longer struggle in cramming Biochemistry but rather find the subject interesting. I wish I started using your lecture guide early in Medical school, but any way not yet late! Thank you once again.
Very dense lecture. Maybe a bit too in-depth in some places, but excellent discussion about the importance of carbohydrates and the key enzymes and reactions that underly the process.
Awesome lectures by Sir. he explain every step and every single reaction with detail thank u.