Arterial Diseases – Buerger's and Raynaud's Disease

by Joseph Alpert, MD

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    Hello. Welcome to the next session of "Vascular Medicine: The Advanced Series." In this session, we're going to be talking about two less common forms of arterial disease: Buerger's disease and Raynaud's disease. Let's first talk about Buerger's disease. Its Latin name is thromboangiitis obliterans, and you can see with the "itis" in there that it's an inflammatory disease having to do with thrombosis and obliterating blood vessels. So let's talk about the definition. Thromboangiitis obliterans: It's a form of arterial obstruction, but it affects small and medium-sized arteries (and also the veins, but the arteries in particular) of the hands and the feet. It results from an inflammatory process, which results in scarring of the artery and eventually closing of the artery. You can see, in the angiogram on the left, the arteries don't get out to the fingertips. They die out just before the last digit… the last component of the digit, the last phalanx. And it's not totally clear what... why there is this inflammation, but it's suspected that it's a kind of immune reaction. And it's progressive, and it results actually in death of tissue on the tips of the fingers and toes, as we'll show you in a moment. The etiology is heavily related to tobacco use. As I mentioned, it's thought to be an autoimmune disease. But it almost only occurs in people who use a lot of cigarettes, a lot of smoking. And as we talked about, it's caused by inflammation and swelling of these small blood vessels that eventually become markedly narrowed or actually close, and it affects mostly the small arteries of the hands and feet. It can affect the arteries in the leg muscles so that there's intermittent claudication, but much more commonly, it presents with gangrene. And you can...

    About the Lecture

    The lecture Arterial Diseases – Buerger's and Raynaud's Disease by Joseph Alpert, MD is from the course Diseases of the Lymphatic System. It contains the following chapters:

    • Buerger's disease - Definition
    • Buerger's disease - Symptoms
    • Raynaud's disease - Definition
    • Raynaud's disease - Symptoms
    • Buerger's- and Raynaud's disease - Summary

    Included Quiz Questions

    1. Autoimmunity and smoking.
    2. Exposure to extreme cold and malnutrition.
    3. Prolonged period of inactivity and carbohydrate rich diet.
    4. Infection and excessive alcohol consumption.
    5. Chronic infection and autoimmunity.
    1. Diminished pulses.
    2. Displaced apex beat.
    3. 3rd heart sound is heard upon auscultation.
    4. Bruit is heard upon auscultation.
    5. Increased pulse pressure.
    1. Reduced vasodilation in effected vessels.
    2. Reduced appreciation of pain.
    3. Reduction in discomfort.
    4. Improved muscle tone.
    5. Altered perception of sensation.
    1. Idiopathic.
    2. Autoimmunity.
    3. Arterial occlusive disease.
    4. Exposure to cold.
    5. Exposure to heat.
    1. 3
    2. 1
    3. 2
    4. 4
    5. 5

    Author of lecture Arterial Diseases – Buerger's and Raynaud's Disease

     Joseph Alpert, MD

    Joseph Alpert, MD

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    Pretty clear, professor …
    By Barbara V. on 27. May 2016 for Arterial Diseases – Buerger's and Raynaud's Disease

    Pretty clear, professor. Is a very pleasure listen to your explanations, remain me my Cubans professors. Thanks