Other Arterial Diseases

by Joseph Alpert, MD

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    Hello. This is advanced vascular medicine. This segment, we'll continue the discussion of arterial diseases. We're going to concentrate, in this section, on further information on dissection of the aorta. And we're also going to talk about renal artery stenosis and fibromuscular dysplasia, which cause abnormalities in renal blood flow and can lead to severe hypertension, which is the topic for our next talk. So let's talk a little bit about dissection of the aorta. I mentioned it in the last talk, when I was discussing aneurysms. But remember: An aneurysm—a true aneurysm—is a dilation and a thinning of the wall of and that… an artery, and eventually, this can lead to rupture. In dissection, that's not the case. What happens in dissection is that there's an actual tear in the inner lining of the heart, allowing the blood and the full blood pressure to gain access to the internal components of the wall of the blood vessel and to dissect down it. And eventually, sometimes, these will rupture through the adventitia and cause hemorrhage, which can be fatal. These conditions—dissections—are caused by a weakened area of elastic and smooth muscle layer tissue in the blood vessel. And again, dissections most commonly occur in the aorta. The most common age group is the 40- to 60-year-old age group. You can see—in this photomicrograph that is taken from a section put under the microscope—you can actually see the rupture, or the tear, in the inner lining—the intima—of this artery. Now, a number… There are a number of risk factors related to the development of dissection. Congenital defects I mentioned in the last lecture, such as bicuspid aortic valve or coarctation of the aorta, are associated with abnormal aortic structure that can lead to a dissection. Marfan's syndrome is another entity where...

    About the Lecture

    The lecture Other Arterial Diseases by Joseph Alpert, MD is from the course Arterial Diseases. It contains the following chapters:

    • Dissection of the aorta - Etiology
    • Dissection of the aorta - Symptoms
    • Dissection of the aorta - Therapy
    • Renal Stenosis and fibromuscular dysplasia
    • Diseases of the arteries - Summary

    Included Quiz Questions

    1. Hypertension
    2. Esophageal spams
    3. Recurrent pneumonia
    4. Peptic ulcers
    1. Severe chest discomfort
    2. Headache
    3. Severe muscle cramps
    4. Uncontrollable diarrhea
    1. The ascending aorta
    2. The descending aorta
    3. The brachial artery
    4. The celiac artery

    Author of lecture Other Arterial Diseases

     Joseph Alpert, MD

    Joseph Alpert, MD

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