by Paul Moss, PhD

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    Welcome to this advanced lecture on the treatment of leukemia. The learning outcomes from this lecture will include the fact that leukaemia represents around 8 percent of all malignant disease. There are four major subsets of leukaemia, but there is great heterogeneity within each of these. The treatment of acute leukaemia is highly effective in younger people, but is very complex and is an area of unmet need in elder individuals. The treatment of chronic leukaemia has shown dramatic improvement in recent years and I look forward to telling you all about that lecture. Leukaemia, the term means white blood. It reflects the fact there are too many tumor cells within the bone marrow and the blood. On the right, you will see a blood slide from the patient with acute leukaemia and those cells are all abnormal tumor cells. The incidence of leukaemia is relatively stable and most subtypes of the disease are seen in all societies around the world. The treatment of leukaemia has changed dramatically in recent years and I would like to communicate some of that excitement to you during the course of this lecture. Let us start with acute leukaemia. Acute leukaemia develops from early haemopoietic progenitor cells, that means cells that give rise to the form cells within the blood and these cells proliferate too rapidly and do not differentiate into later cell types. This is an aggressive disease and it can be rapidly progressive and indeed fatal within the weeks if it is not treated. There are two subsets, lymphoid and myeloid disease and acute lymphoblastic leukaemia is the most common cancer or malignant disease in children. However, although it is a very aggressive disease it can now be cured in many cases. On the right, you will see some of these acute...

    About the Lecture

    The lecture Leukemia by Paul Moss, PhD is from the course Hematology: Advanced. It contains the following chapters:

    • Types of Leukaemia
    • Acute Leukaemia
    • Chronic Leukaemia

    Included Quiz Questions

    1. ATRA
    2. Asparaginase
    3. Steroids
    4. Vincristine
    5. Daunorubicin
    1. Allogeneic bone marrow transplantation is only used in patients with low risk disease.
    2. There is an accumulation of myeloblasts.
    3. Genetic analysis is valuable in predicting the outcome.
    4. It may develop from myelodysplasia.
    5. Stem cell transplantation is more effective when the stem cells are taken from another person (not the patient).
    1. Noticed on a routine blood test
    2. Patient develops indigestion and examination shows a greatly enlarged spleen
    3. Life threatening infection
    4. Severe bleeding
    5. Patient notices some swollen glands in the neck

    Author of lecture Leukemia

     Paul Moss, PhD

    Paul Moss, PhD

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    The crew is awesome …
    By Ever L. on 08. May 2016 for Leukemia

    The crew is awesome ,as soon physiology comes out , I will roll in.....for sure !