Introduction to diseases of the blood system

by Paul Moss, PhD

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    Hello, in this lecture, I'd like to introduce you to the range of diseases that can be seen within the blood system. The outcomes that we'll get from this lecture are quite wide ranging. You'll see that there are many types of disorder that can arise from the blood system and the good way to approach these is to break them down into three different areas: red cells, white cells and disorders of blood clotting which will include platelets and the coagulation factors. We'll see that red cell problems are dominated by anaemia, for which there are many causes. The most important disorders related to white cells are leukaemia and lymphoma and I'll introduce those to you. Finally, platelet disorders and coagulation problems and very different patterns of bleeding and we'll discuss the major causes of these disorders. Let's start with red cells. On the right there you'll see a very beautiful picture of the red cells. Now if there is a reduction in the number of red cells or the haemoglobin concentration in the blood, this is called ANAEMIA. This is a very common disorder and the body becomes deprived of oxygen because of course the major function of red cells is to carry oxygen to the tissues. So the sort of clinical problems that the patient develops are tiredness, shortness of breath, perhaps problems in concentration. Now anaemia may arise because of a decrease in the production of red cells or an increase in the destruction or loss of these cells. Let me try and classify that for you in another way. So here you'll see a diagram showing decreased production of red cells and how that may occur. And at the top in dark green, you'll see 3 categories and in the middle, reduced bone marrow erythroid...

    About the Lecture

    The lecture Introduction to diseases of the blood system by Paul Moss, PhD is from the course Hematology: Basics. It contains the following chapters:

    • Red Cell Disorders
    • White Cell Disorders
    • Additional Malignant Diseases of Blood

    Included Quiz Questions

    1. Acute lymphoblastic leukemia
    2. Chronic lymphoid leukemia
    3. Chronic myeloid leukemia
    4. Acute myeloid leukemia
    5. Acute promyelocytic leukemia
    1. Infection and thrombosis
    2. Infection and fatigue
    3. Lymphadenopathy and bleeding
    4. Infection and shortness of breath
    5. Lymphadenopathy and thrombosis

    Author of lecture Introduction to diseases of the blood system

     Paul Moss, PhD

    Paul Moss, PhD

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