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Glomerular Disease Overview

by Carlo Raj, MD
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    Moving to the glomerular region. Up until this point, what we have done over and over again is giving you an overview as far as laying down the foundation and then we build upon well. With glomerular diseases, first and foremost, think about where you are, you are in the glomerulus and there are numerous issues or factors that may then result in glomerular disease. Let us begin. First and most importantly at this point, is the fact that your operative word here is biopsy. So the fact that you are taking a biopsy specimen based on the symptoms of your patient. Remember once again. Do you remember when we did our session with urinalysis? And with urinalysis, you used information that you had derived based on the history that you got from the patient, either through a clinical vignette or from the attending or what not, and you put all this together so that you can arrive at the proper diagnosis. Well, with the biopsy, there are a couple of important imaging studies that you will have to conduct. You can do an H &E stain and with this, we mean hematoxylin and eosin. And with this, this then allows us to classify the type of glomerular disease. This, for the most part, will be light microscopy. What does light microscopy mean to you? Well, as we go to the various diseases, when it is relevant and pertinent, we will then take a look at diseases in which it is best to classify them through light microscopy. Well, let us say that you don't find exactly as to which you need to or perhaps there is further investigation that is warranted and then you are going to other types of stains and this includes something like immunofluorescence. This is...

    About the Lecture

    The lecture Glomerular Disease Overview by Carlo Raj, MD is from the course Renal Pathology. It contains the following chapters:

    • Glomerular Disorders
    • Electron Microscopy
    • Pathogenesis of Glomerular Disease
    • Mechanisms Producing Glomerular Disease

    Author of lecture Glomerular Disease Overview

     Carlo Raj, MD

    Carlo Raj, MD


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