by Stephen Holt, MD, MS

The spondyloarthritides are a diverse group of distinct yet interrelated disease processes with overlapping clinical features. They comprise ankylosing spondylitis, reactive arthritis, inflammatory bowel disease–associated arthritis, and psoriatic arthritis. Genetically, these disease processes have been linked by the presence of HLA-B27. They manifest with axial and peripheral symptoms, such as inflammatory back pain, enthesitis, oligoarthritis, and dactylitis. The onset of symptoms can begin before the age of 45; however, because of the wide range of signs and symptoms, diagnosis can be delayed, leading to unchecked inflammation, structural damage, and, later, restriction in physical mobility.

Therefore, it is important to suspect spondyloarthritis early on in patients with appropriate history and physical examination findings. Prompt recognition is becoming more important, as effective therapies for early treatment have become available, and it is possible to prevent the debilitating long-term effects of the disease.

Course Details

  • Videos 8
  • Duration 0:38 h
  • Quiz questions 18
  • Concept Pages 3


Your Educators of course Spondyloarthritides

 Stephen Holt, MD, MS

Stephen Holt, MD, MS

Dr. Stephen Holt is the Associate Program Director for Ambulatory Education in the Primary Care Program at the Yale School of Medicine in Connecticut, USA.
He obtained his PhD from Columbia College of Physicians and Surgeons in 2004. Currently, he is Director of the Addiction Recovery Clinic and Codirector of Clinician Educator Distinctions Pathway at Yale School of Medicine.
Because of his achievements, he earned the Faculty Teacher of the Year award from the Yale Primary Care Residency Program in 2009 and 2017.
Within Lecturio, Dr. Holt teaches courses on Physical Examination, Dermatology, and Rheumatology.

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One of the best
By Malakamir M. on 04. September 2021 for Spondyloarthritides

I am going to watch it it again and again, because I learned a lot from him. He knows how to teach and he used a lot of practical examples to explain his lectures.

Lecture is great
By Irfan A. on 06. April 2021 for Spondyloarthritides


Nice overview
By Masooma S. on 23. April 2020 for Spondyloarthritides

I really liked the case based approach, as well as the process of considering different differential diagnosis.

Amazing lectures
By Abdurrahman A. on 19. January 2020 for Spondyloarthritides

All Rhumatology lectures are amazing, and to the point. The way he present, the information, all great.