by Stephen Holt, MD, MS

Rheumatology is the branch of medicine that focuses on the study of rheumatic diseases, which are immune-mediated conditions affecting the joints, ligaments, and muscles. Rheumatic diseases are characterized by soft-tissue inflammation and include immune-mediated and non-immune-mediated arthritis, seronegative spondyloarthropathies, systemic diseases with rheumatic manifestations such as lupus and vasculitides, and muscular pathologies such as Duchenne muscular dystrophy and myasthenia gravis.

Although not as prevalent as other diseases, rheumatic disorders are frequently encountered in clinical practice and are considered important clinical entities given that affected individuals require very specialized care and follow-up. Pharmacological treatments constitute an active research area in this field.

For optimal comprehension, the student should have a thorough understanding of the physiology of the immune system, particularly the mechanisms of humoral and cell-mediated immune responses. Basic knowledge of the histological classification of tissues is desirable as well.

Course Details

  • Videos 67
  • Duration 5:01 h
  • Quiz questions 148
  • Concept Pages 25


Your Educators of course Rheumatology

 Stephen Holt, MD, MS

Stephen Holt, MD, MS

Dr. Stephen Holt is the Associate Program Director for Ambulatory Education in the Primary Care Program at the Yale School of Medicine in Connecticut, USA.
He obtained his PhD from Columbia College of Physicians and Surgeons in 2004. Currently, he is Director of the Addiction Recovery Clinic and Codirector of Clinician Educator Distinctions Pathway at Yale School of Medicine.
Because of his achievements, he earned the Faculty Teacher of the Year award from the Yale Primary Care Residency Program in 2009 and 2017.
Within Lecturio, Dr. Holt teaches courses on Physical Examination, Dermatology, and Rheumatology.

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By Alaena A. on 28. September 2022 for Eosinophilic Granulomatosis with Polyangiitis: Diagnosis and Management

I like the breakdown and explanation of the case. I especially like the discussion of the management which wasn't covered in other lectures.

This lecture makes you want to learn the topic by virtue of its diction/style alone!
By Ruth W. on 01. September 2022 for Cryoglobulinemic Vasculitis

Rendition diction clear and pleasant. Even if you had no particular interest in this topic, just bumped into it, you may become interested because of its diction/style/clarity being so easy/pleasant to learn/hear.

Connective tissue diseases best explained with examples
By Arjit S. on 20. June 2022 for Connective Tissue Diseases

Very lucid explanation and case oriented discussion ....charts and differential diagnosis is excellent

Amazing lecture!
By Weronika W. on 24. October 2021 for Rheuma Case: 59-year-old Man with Bilateral Wrist Pain and Swelling

This is the best way of learning; To go over a case, then break down what to look for in the question stem and give reasons why an answer is incorrect. Thank you so much for these rheumatology cases.