Non-Autoimmune Arthritis
Non-Autoimmune Arthritis

Non-Autoimmune Arthritis

by Stephen Holt, MD, MS

Non-autoimmune arthritides—including osteoarthritis, gout, and septic arthritis—are common diagnoses in primary care settings. It is important to understand the prevalence of specific etiologies and to use the appropriate diagnostic modalities. A delay in diagnosis and treatment, particularly in septic arthritis, can have catastrophic results, including sepsis, bacteremia, joint destruction, or death.

The history and physical examination can help guide the use of laboratory and imaging studies. For example, the presence of focal bone pain or recent trauma requires radiography of the affected joint to rule out metabolic bone disease, tumor, or fracture. If there is a joint effusion in the absence of trauma or recent surgery, and signs of infection (e.g., fever, erythema, warmth) are present, subsequent arthrocentesis should be performed to look for inflammatory synovial fluid containing monosodium urate crystals. Noninflammatory synovial fluid might suggest osteoarthritis or internal derangement.

Pitfalls in the diagnosis and early treatment of non-autoimmune arthritis that must be avoided by the practicing physician include failure to perform arthrocentesis, administering antibiotics before aspirating the joint when septic arthritis is suspected (or failing to start antibiotics after aspiration), and starting treatment based solely on laboratory data, such as an elevated uric acid level.

Course Details

  • Videos 13
  • Duration 0:56 h
  • Quiz questions 30
  • Concept Pages 4


Your Educators of course Non-Autoimmune Arthritis

 Stephen Holt, MD, MS

Stephen Holt, MD, MS

Dr. Stephen Holt is the Associate Program Director for Ambulatory Education in the Primary Care Program at the Yale School of Medicine in Connecticut, USA.
He obtained his PhD from Columbia College of Physicians and Surgeons in 2004. Currently, he is Director of the Addiction Recovery Clinic and Codirector of Clinician Educator Distinctions Pathway at Yale School of Medicine.
Because of his achievements, he earned the Faculty Teacher of the Year award from the Yale Primary Care Residency Program in 2009 and 2017.
Within Lecturio, Dr. Holt teaches courses on Physical Examination, Dermatology, and Rheumatology.

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By Malakamir M. on 04. September 2021 for Non-Autoimmune Arthritis

I am going to watch it it again and again, because I learned a lot from him. He knows how to teach and he used a lot of practical examples to explain his lectures.

very informative lecture
By S C. on 11. August 2021 for Gout: Diagnosis and Treatment

lots of useful and clinically relevant material given in a clear way

Lecture is great
By Irfan A. on 06. April 2021 for Non-Autoimmune Arthritis


By Cerys C. on 10. January 2021 for Rheuma Case: 48-year-old Man with Fevers, R Knee Pain and Swelling

The way the cases are worked through is really good. everything is explained in detail without being overcomplicated.