Connective Tissue Diseases

Connective Tissue Diseases

Connective Tissue Diseases

by Stephen Holt, MD, MS

The connective tissue disorders comprise a number of related conditions, including systemic lupus erythematosus (SLE), antiphospholipid (Hughes) syndrome, scleroderma, myositis, and Sjögren syndrome. They are characterized by autoantibody production and other immune-mediated dysfunctions. There are common clinical and serological features, with some patients having multiple overlapping connective tissue disorders.

Often, these diseases are considered systemic and tend to involve many organ systems, making it extremely important for every physician to be aware of their manifestations. For example, SLE may affect the skin, CNS, heart, lungs, kidneys, and hematopoiesis, among others. Any one of these organs may be the first clinically recognizable manifestation of disease, and prompt therapy can be lifesaving. For these patients, the clinician should obtain a basic history and review of systems, conduct a basic physical examination and laboratory workup, and unerstand when a rheumatology referral might be appropriate.

Course Details

Videos 17
Duration 1:27 h
Quiz questions 43
Concept Pages 6

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Your Educators of course Connective Tissue Diseases

Stephen Holt, MD, MS

Dr. Stephen Holt is the Associate Program Director for Ambulatory Education in the Primary Care Program at the Yale School of Medicine in Connecticut, USA.
He obtained his PhD from Columbia College of Physicians and Surgeons in 2004. Currently, he is Director of the Addiction Recovery Clinic and Codirector of Clinician Educator Distinctions Pathway at Yale School of Medicine.
Because of his achievements, he earned the Faculty Teacher of the Year award from the Yale Primary Care Residency Program in 2009 and 2017.
Within Lecturio, Dr. Holt teaches courses on Physical Examination, Dermatology, and Rheumatology.

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Connective tissue diseases best explained with examples

By Arjit S. on 20. June 2022 for Connective Tissue Diseases

Very lucid explanation and case oriented discussion ....charts and differential diagnosis is excellent

Amazing lecture!

By Weronika W. on 24. October 2021 for Rheuma Case: 59-year-old Man with Bilateral Wrist Pain and Swelling

This is the best way of learning; To go over a case, then break down what to look for in the question stem and give reasons why an answer is incorrect. Thank you so much for these rheumatology cases.

One of the best

By Malakamir M. on 04. September 2021 for Connective Tissue Diseases

I am going to watch it it again and again, because I learned a lot from him. He knows how to teach and he used a lot of practical examples to explain his lectures.

AWESOME REVIEW OF TOPICS

By Vishnu K. on 25. June 2021 for Quick Review: Drug-induced Lupus and Systemic Lupus Erythematosus (SLE)

THANK YOU FOR YOUR MNEUMONICS SIR I WILL NEVER FORGET MED SHIP AND 4SKINRASHNIA

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