Allergic and Immune-mediated Skin Disorders
Allergic and Immune-mediated Skin Disorders

Allergic and Immune-mediated Skin Disorders

by Stephen Holt, MD, MS

The skin is one of the largest immunologic organs. Because of its placement between our external environment and the inside of our bodies, it can be affected by both internal and external factors. It is also a primary line of defense for our bodies, so it only makes sense that it is the site of activity of both innate and adaptive immune responses. Many skin disorders—including dermatitis, urticaria, angioedema, atopic dermatitis, and blistering disorders—are immune mediated. Most of these diseases have chronic courses and fluctuating progression in which genetic and environmental factors are implicated.

Skin disorders are important for any clinician to recognize, as they account for a large percentage of primary care and emergency department visits. Although the morphology of rashes is often difficult to differentiate, it is important to be able to do so, as treatments can vary, and these diseases can result in significant patient morbidity.

Moreover, it is of paramount importance to understand that skin disease can be a window to internal manifestations. Understanding associations between skin diseases—such as psoriasis and its link to cardiovascular disease, or bullous pemphigoid and its link to cancer—can help to guide clinical histories, physical examinations, and management.

Course Details

  • Videos 28
  • Duration 1:40 h
  • Quiz questions 48
  • Concept Pages 23


Your Educators of course Allergic and Immune-mediated Skin Disorders

 Stephen Holt, MD, MS

Stephen Holt, MD, MS

Dr. Stephen Holt is the Associate Program Director for Ambulatory Education in the Primary Care Program at the Yale School of Medicine in Connecticut, USA.
He obtained his PhD from Columbia College of Physicians and Surgeons in 2004. Currently, he is Director of the Addiction Recovery Clinic and Codirector of Clinician Educator Distinctions Pathway at Yale School of Medicine.
Because of his achievements, he earned the Faculty Teacher of the Year award from the Yale Primary Care Residency Program in 2009 and 2017.
Within Lecturio, Dr. Holt teaches courses on Physical Examination, Dermatology, and Rheumatology.

User reviews

4,9 of 5 stars
5 Stars
4 Stars
3 Stars
2 Stars
1  Star
Great instruction
By Steven M. on 14. August 2022 for Allergic and Immune-mediated Skin Disorders

Dr. Holt is a very effective teacher and I learned so much from him.

Dermatology videos.
By SOUMYA D. on 04. July 2022 for Allergic and Immune-mediated Skin Disorders

Loved the concise and crisp approach. Very informative lectures. Helps to get an idea about the topic in a small time

too short but good as an overview
By Daria L. on 05. January 2022 for Anatomy Review: Skin

he didn´t specify where the desmosomes are exactly located

By Malakamir M. on 09. November 2021 for Allergic and Immune-mediated Skin Disorders

I cannot give less than five, Stephen! You merit it!