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MRSA: Nursing Diagnosis

Nursing Knowledge

MRSA: Nursing Diagnosis

Methicillin-resistant Staphylococcus aureus (MRSA) is a type of bacteria that is resistant to many antibiotics commonly used to treat staph infections. MRSA infections can cause severe complications if left untreated, making it an important topic for healthcare professionals, especially nurses. Keep reading to learn about the symptoms of MRSA infections, how they spread, and what can be done to prevent transmission and outbreaks in community settings such as schools and workplaces.
Last updated: September 21, 2026

Table of contents

What is MRSA?

MRSA is a medical diagnosis and a subtype of Staphylococcus aureus that is resistant to beta-lactam antibiotics (penicillins, most cephalosporins and carbapenems).

What are the symptoms of an MRSA infection?

Replace with: Most MRSA infections appear as a red, swollen, or pus-filled bump or infected area in skin or soft tissues.  MRSA can also cause invasive infections that present with systemic symptoms such as fever, hemodynamic instability, and organ-specific findings. 

Nursing diagnoses for MRSA

Potential nursing diagnoses: 

  • Acute pain: pain medication and comfort measures, regular assessments with pain scale
  • Impaired skin integrity: regular wound care with appropriate dressings and prescribed topical treatments
  • Anxiety and deficient knowledge: reassurance and supportive environment, provide clear and accurate information 
  • Risk for infection: contact precautions, environmental decontamination, maintain strict hygiene, monitor for signs of worsening infection, and follow antibiotics administration plan
  • Risk for Impaired thermoregulation/hyperthermia: vigilant temperature monitoring and antipyretic therapy as recommended, fluid and hemodynamic surveillance

How does MRSA spread and what can be done to prevent transmission?

MRSA often spreads by contact with an infected wound or by sharing communal items. To prevent transmission, maintain good hand and body hygiene, keep cuts and wounds clean and covered until fully healed, avoid sharing personal items such as towels or needles, and seek medical evaluation promptly if MRSA infection is suspected.

Transmission and Prevention

Five primary risk factors for the transmission of MRSA involve contact, cleanliness, compromised skin, contaminated objects, and crowded living environments.  The risk for MRSA infection increases with activities that involve sharing equipment such as needles or medical devices, hospitalization, incarceration or surgical patients. 

Essential prevention practices include hand hygiene compliance, contact precautions for colonized/infected patients, environmental cleaning and disinfection, laboratory-based alert systems, and antimicrobial stewardship programs.   

How can MRSA infections be treated?

Incision and drainage (I&D) is a primary treatment for MRSA infections presenting in the skin and soft tissues.  Antibiotics are added with signs of systemic illness, extensive disease, immunosuppression, extremes of age, or failure to respond to I&D alone.  

MRSA infections requiring intravenous antibiotics are usually treated with agents like vancomycin, daptomycin, and linezolid.  Oral antibiotics agents such as trimethoprin-sulfamethoxazole (TMP-SMX), doxycycline/minocycline and clindamycin are more often used for less serious cases.  

If MRSA is causing a skin or soft tissue infection, proper wound care is essential. This might include cleaning the wound, applying dressings, and possibly assisting with procedures like abscess drainage. Follow all infection control protocols to prevent the spread of MRSA to other clients or healthcare workers.

What are some complications that can arise from an untreated MRSA infection?

If left untreated, MRSA infections can lead to fever, sepsis, pneumonia, bloodstream infections, and other severe complications.

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