Cystic Fibrosis

Newborn screening

Epidemiology Etiology and Pathophysiology Etiology Pathophysiology Impact on organ systems Clinical Presentation Respiratory system Gastrointestinal system Small intestine Thick secretions impair absorption, increasing the risk of obstruction. Fails to pass meconium within 48 hrs of life in newborn Constipation, abdominal pain Bowel obstruction, unable to pass gas, abdominal distention, nausea, vomiting Large intestine Incompletely digested […]

Pleuritis

Pleuritis x-ray

Etiology Pathogenesis Clinical Presentation Diagnosis Light’s criteria for pleural effusions Transudate Exudate Protein (pleural/serum) ≤ 0.5 > 0.5 LDH (pleural/serum) ≤ 0.6 > 0.6 Pleural LDH ≤ two-thirds upper limit of normal serum LDH Pleural LDH > two-thirds upper limit of normal serum LDH Common causes Hypoalbuminemia (cirrhosis, nephrotic syndrome) Heart failure Constrictive pericarditis Autoimmune […]

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