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Herpesvirus Humano 6 y 7

Los LOS Neisseria herpesvirus humanos (HHV, por sus siglas en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum inglés)-6 y HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7 son virus Virus Viruses are infectious, obligate intracellular parasites composed of a nucleic acid core surrounded by a protein capsid. Viruses can be either naked (non-enveloped) or enveloped. The classification of viruses is complex and based on many factors, including type and structure of the nucleoid and capsid, the presence of an envelope, the replication cycle, and the host range. Virology similares de ácido desoxirribonucleico (ADN) de doble cadena que pertenecen a la familia Herpesviridae Herpesviridae A family of enveloped, linear, double-stranded DNA viruses infecting a wide variety of animals. Subfamilies, based on biological characteristics, include: alphaherpesvirinae; betaherpesvirinae; and gammaherpesvirinae. Herpes Simplex Virus 1 and 2. Los LOS Neisseria herpesvirus humanos son ubicuos y las infecciones suelen contraerse durante la infancia. Tanto el HHV-6 HHV-6 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7 como el HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7 causan una enfermedad infantil común conocida como roséola infantil (también conocida como roséola o 6ta enfermedad). La roséola es una enfermedad autolimitada que se presenta con fiebre alta, seguida de una erupción maculopapular Maculopapular Dermatologic Examination difusa de color rosa. El diagnóstico es clínico y el tratamiento es de soporte.

Last updated: Dec 15, 2025

Editorial responsibility: Stanley Oiseth, Lindsay Jones, Evelin Maza

Clasificación

Diagrama de flujo de la clasificación de los virus del ADN

Identificación de virus de ADN:
Los virus pueden clasificarse de muchas maneras. Sin embargo, la mayoría de los virus tienen un genoma formado por ADN o ácido ribonucleico (ARN). Los virus con un genoma de ADN pueden caracterizarse además como de cadena simple o doble. Los virus “envueltos” están cubiertos por una fina capa de membrana celular, que suele tomarse de la célula huésped. Sin embargo, si la capa está ausente, los virus se denominan “desnudos”. Algunos virus con envoltura traducen el ADN en ARN antes de incorporarse al genoma de la célula huésped.

Imagen por Lecturio. Licencia: CC BY-NC-SA 4.0

Características Generales y Epidemiología

Características básicas del HHV-6 HHV-6 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7 y del HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7

  • Taxonomía:
    • Familia: Herpesviridae Herpesviridae A family of enveloped, linear, double-stranded DNA viruses infecting a wide variety of animals. Subfamilies, based on biological characteristics, include: alphaherpesvirinae; betaherpesvirinae; and gammaherpesvirinae. Herpes Simplex Virus 1 and 2
    • Subfamilia: Betaherpesvirinae Betaherpesvirinae A subfamily of herpesviridae characterized by a relatively long replication cycle. Genera include: cytomegalovirus; muromegalovirus; and roseolovirus. Cytomegalovirus
    • Género: Roseolovirus Roseolovirus A genus of the family herpesviridae, subfamily betaherpesvirinae, whose viruses have been isolated from lymphocytes. Herpesvirus 6, human is the type species. Human Herpesvirus 6 and 7
    • Especies:
      • Betaherpesvirus humano 6A
      • Betaherpesvirus humano 6B
      • Betaherpesvirus humano 7
  • Virus Virus Viruses are infectious, obligate intracellular parasites composed of a nucleic acid core surrounded by a protein capsid. Viruses can be either naked (non-enveloped) or enveloped. The classification of viruses is complex and based on many factors, including type and structure of the nucleoid and capsid, the presence of an envelope, the replication cycle, and the host range. Virology de ADN:
    • Lineal
    • Doble cadena
  • Estructura:
    • Núcleo de ADN
    • Cápside icosaédrica
    • Tegumento
    • Envoltura lipídica con picos de glicoproteínas
Herpesvirus humano 6

Micrografía electrónica de los viriones del HHV-6

Imagen: “Electron micrograph of one of the HHV6 species” por Bernard Kramarsky. Licencia: Dominio Público

Enfermedades asociadas

La relevancia clínica del HHV-6A no se conoce del todo.

  • El HHV-6B y el HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7 están asociados a:
    • Roséola infantil (también conocida como exantema súbito, roséola o 6ta enfermedad)
    • Enfermedad respiratoria febril aguda
    • Convulsiones febriles
    • Síndromes de reactivación en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum receptores de trasplantes:
    • Es posible:
      • Pitiriasis rosada
      • Liquen plano ( HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7)

Epidemiología

  • HHV-6 HHV-6 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7:
    • > 70% de los LOS Neisseria adultos son seropositivos.
    • La infección suele producirse a los LOS Neisseria 2 años de edad.
  • HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7:
    • > 95% de los LOS Neisseria adultos son seropositivos.
    • La infección suele producirse en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la infancia.

Patogénesis

Reservorio

Los LOS Neisseria humanos son el reservorio del HHV-6 HHV-6 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7 y del HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7.

Transmisión

El HHV-6 HHV-6 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7 y el HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7 se transmiten por contacto con la saliva Saliva The clear, viscous fluid secreted by the salivary glands and mucous glands of the mouth. It contains mucins, water, organic salts, and ptyalin. Salivary Glands: Anatomy.

Fisiopatología

  • La replicación se produce en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum los LOS Neisseria linfocitos T.
  • Entrada viral a través de:
    • HHV-6 HHV-6 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7: receptor Receptor Receptors are proteins located either on the surface of or within a cell that can bind to signaling molecules known as ligands (e.g., hormones) and cause some type of response within the cell. Receptors CD46
    • HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7: receptor Receptor Receptors are proteins located either on the surface of or within a cell that can bind to signaling molecules known as ligands (e.g., hormones) and cause some type of response within the cell. Receptors CD4
  • El ADN viral se libera en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el nucleoplasma → producción de proteínas virales y replicación
  • Replicación lítica → muerte celular
  • Niveles bajos de infección persistente se produce en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum las glándulas salivales.
  • Latencia:
    • HHV-6 HHV-6 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7: ocurre en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum los LOS Neisseria monocitos
    • HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7: ocurre en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum los LOS Neisseria linfocitos T

Presentación Clínica

Las infecciones por herpesvirus humano 6 suelen ser leves y se producen durante la infancia. La mayoría de las infecciones por HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7 son asintomáticas.

Roséola infantil

  • Fiebre alta:
    • Dura aproximadamente 3–5 días
    • Se resuelve abruptamente
  • Erupción:
    • Duración:
      • Aparece luego de la resolución de la fiebre
      • Dura aproximadamente 1–2 días
    • Apariencia:
    • No pruriginoso
    • Distribución:
      • Comienza en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el cuello y el tronco
      • Se extiende a la cara y a las extremidades
  • Otras manifestaciones:
    • Conjuntivitis
    • Párpados edematosos
    • Otitis media
    • Manchas de Nagayama (pápulas uvulopalatoglosas eritematosas)
    • Rinorrea
    • Tos TOS Thoracic outlet syndrome (TOS) is a broad term used for a spectrum of syndromes related to the general region of the thoracic outlet, which involves the compression or irritation of elements of the brachial plexus, subclavian artery, or subclavian vein. Thoracic Outlet Syndrome
    • Diarrea
    • Vómitos
    • Fontanela abultada
    • Linfadenopatía:
      • Cervical
      • Postauricular
      • Occipital Occipital Part of the back and base of the cranium that encloses the foramen magnum. Skull: Anatomy

Diagnóstico y Tratamiento

Diagnóstico

El diagnóstico es clínico y rara vez están indicadas pruebas. Se hace HACE Altitude Sickness una excepción en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum caso de enfermedad grave en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum individuos inmunocomprometidos (e.g., encefalitis, miocarditis).

  • Reacción en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum cadena de polimerasa ( PCR PCR Polymerase chain reaction (PCR) is a technique that amplifies DNA fragments exponentially for analysis. The process is highly specific, allowing for the targeting of specific genomic sequences, even with minuscule sample amounts. The PCR cycles multiple times through 3 phases: denaturation of the template DNA, annealing of a specific primer to the individual DNA strands, and synthesis/elongation of new DNA molecules. Polymerase Chain Reaction (PCR), por sus siglas en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum inglés) para detectar el ADN viral
  • Serología
    • Inmunofluorescencia indirecta
    • Ensayo inmunoabsorbente ligado a enzimas ( ELISA ELISA An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed. St. Louis Encephalitis Virus, por sus siglas en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum inglés)

Tratamiento

Por lo general, no es necesario el tratamiento, ya que los LOS Neisseria síntomas son autolimitados. Se puede administrar a los LOS Neisseria pacientes con enfermedad grave:

  • Ganciclovir Ganciclovir An acyclovir analog that is a potent inhibitor of the herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from aids-associated cytomegalovirus infections. Antivirals for Herpes Virus
  • Cidofovir Cidofovir An acyclic nucleoside phosphonate that acts as a competitive inhibitor of viral DNA polymerases. It is used in the treatment of retinitis caused by cytomegalovirus infections and may also be useful for treating herpesvirus infections. Antivirals for Herpes Virus
  • Foscarnet Foscarnet An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV. Antivirals for Herpes Virus
  • Nota: Los LOS Neisseria datos de estos tratamientos son limitados.

Comparación de los Herpesvirus

La siguiente tabla compara los LOS Neisseria 9 herpesvirus considerados endémicos en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el ser humano; en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum total se conocen 115 especies diferentes de herpesvirus, agrupadas en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum 3 familias:

  • Alfa (infectan a las células epiteliales y producen una infección latente en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum las neuronas postmitóticas)
  • Beta (infectan y producen una infección latente en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum una variedad de tipos de células)
  • Gamma (producen una infección latente, principalmente en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum las células linfoides)
Tabla: Comparación de los LOS Neisseria 9 herpesvirus considerados endémicos en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum humanos
HHV Nombre común Células diana primarias Sitio de latencia Presentación clínica*
1
(grupo alfa)
HSV-1 Células mucoepiteliales Ganglios de la raíz dorsal
  • Gingivoestomatitis
  • Queratitis
  • Panadizo herpético
  • Encefalitis
  • Hepatitis
  • Esofagitis
  • Neumonitis
2
(grupo alfa)
HSV-2
  • Herpes genital
  • Meningitis Meningitis Meningitis is inflammation of the meninges, the protective membranes of the brain, and spinal cord. The causes of meningitis are varied, with the most common being bacterial or viral infection. The classic presentation of meningitis is a triad of fever, altered mental status, and nuchal rigidity. Meningitis
  • Proctitis Proctitis Inflammation of the mucous membrane of the rectum, the distal end of the large intestine. Chronic Granulomatous Disease
3
(grupo alfa)
VZV
  • Varicela
  • Herpes zóster
4
(grupo gamma)
EBV EBV Epstein-barr virus (EBV) is a linear, double-stranded DNA virus belonging to the herpesviridae family. This highly prevalent virus is mostly transmitted through contact with oropharyngeal secretions from an infected individual. The virus can infect epithelial cells and B lymphocytes, where it can undergo lytic replication or latency. Epstein-Barr Virus
  • Células epiteliales
  • Células B
Células B de memoria
  • Mononucleosis Mononucleosis Infectious mononucleosis (IM), also known as “the kissing disease,” is a highly contagious viral infection caused by the Epstein-Barr virus. Its common name is derived from its main method of transmission: the spread of infected saliva via kissing. Clinical manifestations of IM include fever, tonsillar pharyngitis, and lymphadenopathy. Mononucleosis infecciosa
  • Linfoma de Hodgkin
  • Linfoma de Burkitt
  • Leucoplasia vellosa oral
  • Cáncer gástrico asociado al AL Amyloidosis EBV EBV Epstein-barr virus (EBV) is a linear, double-stranded DNA virus belonging to the herpesviridae family. This highly prevalent virus is mostly transmitted through contact with oropharyngeal secretions from an infected individual. The virus can infect epithelial cells and B lymphocytes, where it can undergo lytic replication or latency. Epstein-Barr Virus
5
(grupo beta)
CMV
  • Monocitos
  • Linfocitos
  • Células epiteliales
Células progenitoras hematopoyéticas en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la médula ósea
  • Mononucleosis Mononucleosis Infectious mononucleosis (IM), also known as “the kissing disease,” is a highly contagious viral infection caused by the Epstein-Barr virus. Its common name is derived from its main method of transmission: the spread of infected saliva via kissing. Clinical manifestations of IM include fever, tonsillar pharyngitis, and lymphadenopathy. Mononucleosis por CMV
  • Retinitis por CMV
  • Colitis Colitis Inflammation of the colon section of the large intestine, usually with symptoms such as diarrhea (often with blood and mucus), abdominal pain, and fever. Pseudomembranous Colitis por CMV
  • Encefalitis por CMV
6A, 6B
(grupo beta)
HHV-6 HHV-6 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7 Células T Monocitos Roséola
7
(grupo beta)
HHV-7 HHV-7 Human herpesvirus (HHV)-6 and HHV-7 are similar double-stranded DNA viruses belonging to the Herpesviridae family. Human herpesviruses are ubiquitous and infections are commonly contracted during childhood. Human Herpesvirus 6 and 7 Células T
8
(grupo gamma)
Herpesvirus asociado al AL Amyloidosis sarcoma de Kaposi Kaposi A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Hhv-8 is the suspected cause. There is also a high incidence in AIDS patients. AIDS-defining Conditions
  • Linfocitos
  • Células epiteliales
Células B Sarcoma de Kaposi Kaposi A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Hhv-8 is the suspected cause. There is also a high incidence in AIDS patients. AIDS-defining Conditions
La negrita en la columna de “presentación clínica” denota una enfermedad definitoria de síndrome de inmunodeficiencia adquirida (SIDA).
CMV: citomegalovirus
EBV: virus de Epstein-Barr
HHV: herpesvirus humano
HSV: virus del herpes simple
KSHV: herpesvirus asociado al sarcoma de Kaposi
VZV: virus de la varicela-zóster

Comparación de las Erupciones Infantiles Más Comunes

Tabla: Comparación de las erupciones comunes en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la infancia
Número Otros nombres de la enfermedad Etiología Descripción
1ra enfermedad
  • Sarampión
  • Rubeola Rubeola Measles (also known as rubeola) is caused by a single-stranded, linear, negative-sense RNA virus of the family Paramyxoviridae. It is highly contagious and spreads by respiratory droplets or direct-contact transmission from an infected person. Typically a disease of childhood, measles classically starts with cough, coryza, and conjunctivitis, followed by a maculopapular rash. Measles Virus
  • Sarampión de 14 días
  • Morbilli Morbilli Measles (also known as rubeola) is caused by a single-stranded, linear, negative-sense RNA virus of the family Paramyxoviridae. It is highly contagious and spreads by respiratory droplets or direct-contact transmission from an infected person. Typically a disease of childhood, measles classically starts with cough, coryza, and conjunctivitis, followed by a maculopapular rash. Measles Virus
Morbillivirus Morbillivirus A genus of the family paramyxoviridae (subfamily paramyxovirinae) where the virions of most members have hemagglutinin but not neuraminidase activity. All members produce both cytoplasmic and intranuclear inclusion bodies. Measles virus is the type species. Measles Virus del sarampión
  • Tos TOS Thoracic outlet syndrome (TOS) is a broad term used for a spectrum of syndromes related to the general region of the thoracic outlet, which involves the compression or irritation of elements of the brachial plexus, subclavian artery, or subclavian vein. Thoracic Outlet Syndrome, coriza, conjuntivitis
  • Manchas de Koplik (manchas blanco-azuladas con un halo rojo) en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la membrana bucal
  • La erupción maculopapular Maculopapular Dermatologic Examination comienza en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la cara y detrás de las orejas → se extiende al AL Amyloidosis tronco/las extremidades
2da enfermedad
  • Fiebre escarlata
  • Escarlatina
Streptococcus Streptococcus Streptococcus is one of the two medically important genera of gram-positive cocci, the other being Staphylococcus. Streptococci are identified as different species on blood agar on the basis of their hemolytic pattern and sensitivity to optochin and bacitracin. There are many pathogenic species of streptococci, including S. pyogenes, S. agalactiae, S. pneumoniae, and the viridans streptococci. Streptococcus pyogenes
  • Erupción maculopapular Maculopapular Dermatologic Examination con sensación de papel de lija que comienza en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el cuello y la ingle → se extiende al AL Amyloidosis tronco/las extremidades
  • Zonas oscuras e hiperpigmentadas, especialmente en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum los LOS Neisseria pliegues de la piel, llamadas líneas de Pastia
  • Lengua de fresa: membrana blanca recubierta a través de la cual sobresalen papilas inflamadas y rojas
3ra enfermedad
  • Rubeola Rubeola Measles (also known as rubeola) is caused by a single-stranded, linear, negative-sense RNA virus of the family Paramyxoviridae. It is highly contagious and spreads by respiratory droplets or direct-contact transmission from an infected person. Typically a disease of childhood, measles classically starts with cough, coryza, and conjunctivitis, followed by a maculopapular rash. Measles Virus
  • Sarampión alemán
  • Sarampión de 3 días
Virus Virus Viruses are infectious, obligate intracellular parasites composed of a nucleic acid core surrounded by a protein capsid. Viruses can be either naked (non-enveloped) or enveloped. The classification of viruses is complex and based on many factors, including type and structure of the nucleoid and capsid, the presence of an envelope, the replication cycle, and the host range. Virology de la rubéola
  • Asintomático en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el 50% de los LOS Neisseria casos
  • Erupción macular fina en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la cara (detrás de las orejas) → se extiende al AL Amyloidosis cuello, al AL Amyloidosis tronco y a las extremidades (respeta las palmas de las manos y las plantas de los LOS Neisseria pies)
  • Manchas de Forscheimer: Pueden verse máculas rojas puntiformes y petequias sobre el paladar blando/la úvula.
  • Linfadenopatía sensible generalizada
4ta enfermedad
  • Síndrome de la piel escaldada por estafilococos
  • Enfermedad de Filatow-Dukes
  • Enfermedad de Ritter
Debido a las cepas de Staphylococcus aureus Staphylococcus aureus Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications. Brain Abscess que fabrican la toxina epidermolítica (exfoliativa)
  • Algunos creen que la 4ta enfermedad es un diagnóstico erróneo y, por tanto, inexistente.
  • El término se abandonó en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la década de 1960 y en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la actualidad sólo se utiliza para trivialidades médicas.
  • Comienza con una erupción eritematosa difusa que suele empezar alrededor de la boca → bullas llenas de líquido o ampollas cutáneas → se rompen y descaman
  • Signo de Nikolsky: La aplicación de presión sobre la piel con un dedo (caricias) provoca la descamación de las capas superiores.
5ta enfermedad Eritema infeccioso Eritrovirus o parvovirus B19 Parvovirus B19 Primate erythroparvovirus 1 (generally referred to as parvovirus B19, B19 virus, or sometimes erythrovirus B19) ranks among the smallest DNA viruses. Parvovirus B19 is of the family Parvoviridae and genus Erythrovirus. In immunocompetent humans, parvovirus B19 classically results in erythema infectiosum (5th disease) or “slapped cheek syndrome.” Parvovirus B19 (eritroparvovirus 1 de los LOS Neisseria primates)
  • Eritema facial (erupción de “mejillas abofeteadas”) que consiste en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum pápulas rojas en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum las mejillas
  • Comienza en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la cara → se extiende a las extremidades → se extiende al AL Amyloidosis tronco/glúteos
  • Inicialmente confluente, luego se convierte en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum forma de red o reticular al AL Amyloidosis aclararse
6ta enfermedad
  • Exantema súbito
  • Roséola infantil
  • Erupción rosada de los LOS Neisseria lactantes
  • Fiebre de 3 días
Herpesvirus humano 6B o 7
  • Aparición repentina de fiebre alta
  • Manchas de Nagayama: manchas papulares en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el paladar blando/úvula
  • La erupción comienza cuando la fiebre se resuelve (el término “exantema súbito” describe la “sorpresa” de la erupción después de que la fiebre cede).
  • Numerosas máculas de color rosa, en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum forma de almendra, en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el tronco y el cuello → a veces se extiende a la cara/extremidades

Referencias

  1. Tremblay, C. (2024). Virology, pathogenesis, and epidemiology of human herpesvirus 6 infection. In Bond, S. (Ed.), UpToDate. Retrieved November 18, 2025, from https://www.uptodate.com/contents/virology-pathogenesis-and-epidemiology-of-human-herpesvirus-6-infection
  2. Tremblay, C., Brady, M.T. (2024). Human herpesvirus 6 infection in children: Clinical manifestations, diagnosis, and treatment. In Torchia, M.M. (Ed.), UpToDate. Retrieved November 18, 2025, from https://www.uptodate.com/contents/human-herpesvirus-6-infection-in-children-clinical-manifestations-diagnosis-and-treatment
  3. Tremblay, C. (2025). Clinical manifestations, diagnosis, and treatment of human herpesvirus 6 infection in adults. In Bond, S. (Ed.), UpToDate. Retrieved November 18, 2025, from https://www.uptodate.com/contents/clinical-manifestations-diagnosis-and-treatment-of-human-herpesvirus-6-infection-in-adults
  4. Tremblay, C. (2025). Human herpesvirus 7 infection. In Bond, S. (Ed.), UpToDate. Retrieved November 18, 2025, from https://www.uptodate.com/contents/human-herpesvirus-7-infection
  5. Tesini, B.L. (2023). Roseola infantum. [online] MSD Manual Professional Version. Retrieved November 18, 2025, from https://www.msdmanuals.com/professional/pediatrics/miscellaneous-viral-infections-in-infants-and-children/roseola-infantum
  6. King, O., Al Khalili, Y. (2025). Herpes virus type 6. [online] StatPearls. Retrieved November 18, 2025, from https://www.ncbi.nlm.nih.gov/books/NBK540998/
  7. Mullins, T.B., Krishnamurthy, K. (2023). Roseola infantum. [online] StatPearls. Retrieved November 18, 2025, from https://www.ncbi.nlm.nih.gov/books/NBK448190/
  8. Kiley, J.L., Blyth, D.M. (2024). Human herpesvirus 6 (HHV-6) infection. In Chandrasekar, P.H. (Ed.), Medscape. Retrieved November 18, 2025, from https://emedicine.medscape.com/article/219019-overview
  9. Wolz, M.M., Sciallis, G.F., Pittelkow, M.K. (2012). Human herpesviruses 6, 7, and 8 from a dermatologic perspective. In Mayo Clinical Proceedings. 87(10):1004-1014. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538396/

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