Virus de la Hepatitis C

Clasificación

Características Generales

Estructura

• Taxonomía:
  • Familia: Flaviviridae Flaviviridae A family of RNA viruses, many of which cause disease in humans and domestic animals. There are three genera flavivirus; pestivirus; and hepacivirus, as well as several unassigned species. Hepatitis C Virus
  • Género: Hepacivirus Hepacivirus A genus of flaviviridae causing parenterally-transmitted hepatitis C which is associated with transfusions and drug abuse. Hepatitis c virus is the type species. Hepatitis C Virus
• ARN de cadena simple y de sentido positivo
• El genoma está formado por un único marco de lectura abierto de 9 600 bases Bases Usually a hydroxide of lithium, sodium, potassium, rubidium or cesium, but also the carbonates of these metals, ammonia, and the amines. Acid-Base Balance de nucleótidos.
• Pequeño (55–65 nm)
• Esférico
• Envuelto: membrana lipídica con 2 glicoproteínas ( E1 E1 An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from androstenedione directly, or from testosterone via estradiol. In humans, it is produced primarily by the cyclic ovaries, placenta, and the adipose tissue of men and postmenopausal women. Noncontraceptive Estrogen and Progestins y E2) incrustadas → desempeñan un papel en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la fijación del virus Virus Viruses are infectious, obligate intracellular parasites composed of a nucleic acid core surrounded by a protein capsid. Viruses can be either naked (non-enveloped) or enveloped. The classification of viruses is complex and based on many factors, including type and structure of the nucleoid and capsid, the presence of an envelope, the replication cycle, and the host range. Virology a la célula huésped

Características

• Periodo de incubación: 2 semanas–6 meses (periodo medio de incubación: 8 semanas)
• Puede causar hepatitis aguda y crónica
• La razón más común para el trasplante de hígado

Epidemiología

• Prevalencia:
  • Alrededor de 70 millones de personas en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el mundo tienen hepatitis C Hepatitis C Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C virus can cause both acute and chronic hepatitis, ranging from a mild to a serious, lifelong illness including liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis C Virus crónica.
  • Solo un 20% de las personas infectadas por el virus Virus Viruses are infectious, obligate intracellular parasites composed of a nucleic acid core surrounded by a protein capsid. Viruses can be either naked (non-enveloped) or enveloped. The classification of viruses is complex and based on many factors, including type and structure of the nucleoid and capsid, the presence of an envelope, the replication cycle, and the host range. Virology de la hepatitis C Hepatitis C Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C virus can cause both acute and chronic hepatitis, ranging from a mild to a serious, lifelong illness including liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis C Virus ( HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus) conocen su diagnóstico.
  • Solo alrededor del 60% de las personas con infecciones crónicas reciben un tratamiento adecuado.
  • Regiones con mayor prevalencia:
    • Mediterráneo Oriental
    • Sudeste de Asia ASIA Spinal Cord Injuries
    • Pacífico Occidental
    • África Subsahariana
• Alrededor de 290 000 muertes al AL Amyloidosis año
• El HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus es la causa más común de hepatitis crónica en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum Estados Unidos.
• Los LOS Neisseria genotipos se agrupan por ubicación:
  • Genotipo 1: Estados Unidos y norte de Europa (45%–55%)
  • Genotipo 2: Países mediterráneos (80%–90%)
  • Genotipo 3: Subcontinente indio (70%–85%)
  • Genotipo 4: Egipto y África del Norte (50%–60%)

Patogénesis

Transmisión

Los LOS Neisseria humanos son el único reservorio del virus Virus Viruses are infectious, obligate intracellular parasites composed of a nucleic acid core surrounded by a protein capsid. Viruses can be either naked (non-enveloped) or enveloped. The classification of viruses is complex and based on many factors, including type and structure of the nucleoid and capsid, the presence of an envelope, the replication cycle, and the host range. Virology. Los LOS Neisseria modos de transmisión incluyen:

• Parenteral
• Sexual
• Perinatal
• Tatuajes, compartir maquinillas de afeitar y reutilizar agujas de acupuntura

Factores de riesgo del huésped

• Personas que se inyectan drogas → las agujas no estériles y el uso compartido de agujas suponen el mayor riesgo de infección por el HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus
• Hombres que tienen sexo con hombres
• El tamizaje de la sangre donada para detectar los LOS Neisseria anticuerpos contra el HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus ↓ marcadamente el riesgo de infección por el HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus asociada a la transfusión.
• Trabajadores sanitarios u otras exposiciones profesionales (lesiones por pinchazos)

Fisiopatología

• La entrada en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum las células del huésped se produce a través de las glicoproteínas de la superficie del virión
• Las interacciones proteína– receptor Receptor Receptors are proteins located either on the surface of or within a cell that can bind to signaling molecules known as ligands (e.g., hormones) and cause some type of response within the cell. Receptors conducen a la endocitosis de la partícula viral (ayudada por las proteínas clatrina)
• Entra en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el endosoma → el endosoma y la envoltura viral se fusionan → el ARN entra en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el citoplasma
• El HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus controla la maquinaria intracelular de la célula huésped para replicarse → genoma del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus traducido
• La replicación del ARN tiene lugar a través de la ARN polimerasa viral dependiente del ARN
• El ARN de cadena negativa actúa como una plantilla para la producción de nuevos genomas virales de cadena positiva
• El ARN naciente puede entonces traducirse, seguir replicándose o empaquetarse en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum nuevas partículas de virus Virus Viruses are infectious, obligate intracellular parasites composed of a nucleic acid core surrounded by a protein capsid. Viruses can be either naked (non-enveloped) or enveloped. The classification of viruses is complex and based on many factors, including type and structure of the nucleoid and capsid, the presence of an envelope, the replication cycle, and the host range. Virology.

Presentación Clínica

Infección aguda

• A menudo asintomática
• Si está presente, los LOS Neisseria síntomas pueden incluir:
  • Ictericia
  • Fatiga
  • Artralgias, mialgias
  • Dolor Dolor Inflammation abdominal
  • Fiebre
  • Náuseas, vómitos, diarrea
  • Muy raro: enfermedad grave con insuficiencia hepática aguda

Infección crónica

• El 60%–85% de las personas infectadas desarrollan una infección crónica por el HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus.
• Alrededor de 1 de cada 5 infecciones acaba en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum cirrosis en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum un plazo de 20 años.
• Síntomas: la mayoría de los LOS Neisseria síntomas son inespecíficos y similares a los LOS Neisseria de una infección aguda
• Cirrosis hepática
• Manifestaciones extrahepáticas:
  • Hematológicas:
    • Crioglobulinemia
    • Linfoma
  • Endocrinas:
    • Diabetes Diabetes Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia and dysfunction of the regulation of glucose metabolism by insulin. Type 1 DM is diagnosed mostly in children and young adults as the result of autoimmune destruction of β cells in the pancreas and the resulting lack of insulin. Type 2 DM has a significant association with obesity and is characterized by insulin resistance. Diabetes Mellitus mellitus
    • Tiroiditis autoinmune
  • Renal: glomerulonefritis
  • Dermatológicas:
    • Eritema nodoso
    • Porfiria cutánea tardía
    • Liquen plano

Diagnóstico

Marcadores virales

• Anticuerpos del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus:
  • Prueba inicial
  • Los LOS Neisseria resultados positivos no permiten diferenciar entre una infección aguda, crónica o previa por el HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus.
  • Puede detectarse 7–8 semanas después de la infección inicial
  • Resultado positivo → confirmar la infección actual mediante la prueba de ARN del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus
  • Prueba de anticuerpos del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus negativa, pero sospecha clínica → prueba de ARN del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus o repetición de la prueba de anticuerpos del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus
• ARN del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus:
  • Se realiza después de un resultado positivo de anticuerpos contra el HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus
  • Indica infección activa (aguda o crónica)
  • Realizar siempre la prueba del ARN del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum lugar de los LOS Neisseria anticuerpos del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum los LOS Neisseria siguientes casos:
    • Inmunosupresión
    • Infección por virus Virus Viruses are infectious, obligate intracellular parasites composed of a nucleic acid core surrounded by a protein capsid. Viruses can be either naked (non-enveloped) or enveloped. The classification of viruses is complex and based on many factors, including type and structure of the nucleoid and capsid, the presence of an envelope, the replication cycle, and the host range. Virology de inmunodeficiencia humana (VIH)
    • Personas en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum diálisis

Pruebas adicionales

• Las transaminasas alanina aminotransferasa/aspartato aminotransferasa pueden estar ↑
• Parámetros de colestasis: γ-glutamil transferasa, fosfatasa alcalina, bilirrubina, pueden estar ↑
• Albúmina, colinesterasa pueden estar ↓
• Ultrasonido y elastografía hepática → evaluar la cirrosis y el carcinoma hepatocelular

Tratamiento

Farmacoterapia

• Indicación: cualquier infección replicativa del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus (= ARN del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus detectable)
• Cuantificar el ARN del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus antes de iniciar el tratamiento antiviral Antiviral Antivirals for Hepatitis B para obtener la carga viral de referencia
• Alrededor del 30% de los LOS Neisseria individuos infectados eliminan espontáneamente la infección debido a una fuerte respuesta inmunitaria → no necesitan tratamiento
• Objetivos del tratamiento:
  • Erradicación del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus (definida como la ausencia persistente de ARN del HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el suero 12 semanas después de completar el tratamiento antiviral Antiviral Antivirals for Hepatitis B)
  • Prevención de la progresión hacia cirrosis, carcinoma hepatocelular y la enfermedad hepática descompensada que requiere un trasplante de hígado
• Combinación de 2 agentes antivirales de acción directa en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum función de los LOS Neisseria genotipos:
  • Ejemplos:
    • Glecaprevir Glecaprevir Antivirals for Hepatitis C + pibrentasvir Pibrentasvir Antivirals for Hepatitis C
    • Ledipasvir Ledipasvir Antivirals for Hepatitis C + sofosbuvir
    • Sofosbuvir + velpatasvir Velpatasvir Antivirals for Hepatitis C
    • Elbasvir Elbasvir Antivirals for Hepatitis C + grazoprevir Grazoprevir Antivirals for Hepatitis C
  • Administrado durante 8-24 semanas, dependiendo de la presencia y gravedad de la cirrosis
• El interferón y la ribavirina suelen evitarse en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la actualidad debido a sus efectos secundarios.

Prevención

• No hay vacuna disponible
• No se dispone de profilaxis previa o posterior a la exposición
• La prevención se centra en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum reducir el riesgo de exposición:
  • Educar a las poblaciones de alto riesgo de infección (personas que se inyectan drogas, hombres que tienen sexo con hombres, personas infectadas con VIH)
  • Uso seguro de las inyecciones sanitarias
  • Manipulación y eliminación segura de objetos punzantes y residuos
  • Análisis de las donaciones de sangre para detectar el HCV HCV Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Hepatitis C virus is an RNA virus and a member of the genus Hepacivirus and the family Flaviviridae. The infection can be transmitted through infectious blood or body fluids and may be transmitted during childbirth or through IV drug use or sexual intercourse. Hepatitis C Virus

Cuadro Comparativo de los Virus de la Hepatitis

Diagnóstico Diferencial

• Enfermedad hepática alcohólica: patología hepática que se produce por el consumo excesivo y prolongado de alcohol. La 1ra etapa es un hígado graso asintomático, que es reversible. La 2da etapa es la hepatitis alcohólica, que suele presentarse con ictericia, fiebre y dolor Dolor Inflammation en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la región abdominal. La 3ra etapa es la cirrosis hepática. El diagnóstico se establece mediante los LOS Neisseria antecedentes clínicos, pruebas de función hepática e imagenología.
• Lesión hepática inducida por medicamentos: se produce cuando los LOS Neisseria medicamentos ingeridos causan lesiones en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum los LOS Neisseria hepatocitos directamente de forma predecible y dependiente de la dosis o a través de reacciones idiosincrásicas. La presentación de la lesión hepática inducida por medicamentos puede ser aguda o crónica, con una toxicidad grave que se manifiesta como una insuficiencia hepática fulminante. El diagnóstico de la lesión hepática inducida por medicamentos requiere antecedentes detallados y pruebas de laboratorio. El tratamiento consiste en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el diagnóstico precoz y la interrupción del medicamento, así como la terapia de soporte.
• Hepatitis autoinmune: inflamación del hígado que se produce cuando el sistema inmunitario del organismo ataca a sus propias células hepáticas. La presentación clínica va VA Ventilation: Mechanics of Breathing desde lo asintomático hasta los LOS Neisseria síntomas de insuficiencia hepática aguda. El diagnóstico se establece mediante un análisis de sangre para detectar autoanticuerpos característicos (especialmente, anticuerpos contra el músculo liso) y una biopsia de hígado. El tratamiento incluye corticosteroides y azatioprina.
• Enfermedad de Wilson: trastorno autosómico recesivo por una mutación en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el gen ATP7B, que regula el transporte de cobre en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum los LOS Neisseria hepatocitos. Las manifestaciones neuropsiquiátricas de la enfermedad de Wilson ayudan a diferenciarla de otras causas de hepatitis. En EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum las primeras fases, la enfermedad de Wilson puede confundirse con la encefalopatía hepática. Anillos de Kayser-Fleischer, los LOS Neisseria niveles bajos de ceruloplasmina ayudan a separar la enfermedad de Wilson de otras causas de hepatitis.
• Enfermedad del hígado graso no alcohólico: espectro de patología hepática que surge debido a la acumulación de triglicéridos en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum los LOS Neisseria hepatocitos. La enfermedad del hígado graso no alcohólico va VA Ventilation: Mechanics of Breathing desde el hígado graso o la esteatosis hepática hasta la esteatohepatitis no alcohólica, que presenta depósitos grasos e inflamación. La lesión hepática progresiva y la fibrosis Fibrosis Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury. Bronchiolitis Obliterans se convierten irreversiblemente en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum cirrosis y, posiblemente, en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum cáncer primario de hígado. El tratamiento se realiza con modificaciones del estilo de vida (dieta y ejercicio).