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Complement Deficiencies – Primary Immunodeficiency

by Peter Delves, PhD
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    About the Lecture

    The lecture Complement Deficiencies – Primary Immunodeficiency by Peter Delves, PhD is from the course Immunodeficiency and Immune Deficiency Diseases. It contains the following chapters:

    • Complement Deficiencies
    • Paroxysmal Nocturnal Hemoglobinuria
    • Hereditary Angioedema

    Included Quiz Questions

    1. Neisseria meningitidis
    2. Streptococcus pneumoniae
    3. Staphylococcus aereus
    4. Escherichia coli
    5. Candida albicans
    1. C8
    2. Factor I
    3. C1q
    4. C2
    5. C4
    1. GPI anchors attached CD55 and CD59 to the cell surface, which inhibit complement mediated lysis by inhibiting C3 convertase and insertion of the membrane attack complex
    2. GPI anchors inhibit formation of the membrane attack complex and activation of C3 convertase
    3. GPI anchors protect against the actions of CD55 and CD59
    4. GPI anchors inhibit complement mediated lysis by inhibiting CD55 and CD59, which inhibits C3 convertase and the membrane attack complex
    5. GPI anchors attached CD55 and CD59 to the cell surface, attracting C3 convertase which protects against the membrane attack complex

    Author of lecture Complement Deficiencies – Primary Immunodeficiency

     Peter Delves, PhD

    Peter Delves, PhD


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