Thyroid Hormone Function

by Carlo Raj, MD

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    About the Lecture

    The lecture Thyroid Hormone Function by Carlo Raj, MD is from the course Thyroid Gland Disorders.

    Included Quiz Questions

    1. Iodide is transported into follicular cell via sodium-iodide symporter
    2. Sodium is necessary in the forming of the enzyme peroxidase
    3. Sodium helps catalyze the reaction from iodine to iodide
    4. Thyroglobulin transport is dependent on sodium
    5. TSH receptors requiring binding of sodium to transport iodide across the basolateral membrane
    1. Will be unable to peripherally transform T4 to T3
    2. Will be unable to centrally convert iodine to iodine
    3. Will be unable to form complexes with thyroglobulin
    4. Will have low circulating levels of T4
    5. Will have low levels of tyrosine
    1. Amount of anti-thyroglobulin antibodies in serum
    2. Thyroid origin of the biopsied tissue
    3. Mass of thyroid tissue present
    4. Presence of injury to thyroid tissue
    5. Degree of TSH-R stimulation
    1. Methimazole propylthiouracil
    2. RAI
    3. Thiocyanate
    4. rT2 deiodinase
    5. Perchlorate
    1. rT2 deficiency
    2. Grave's disease
    3. Excessive anti-thyroglobulin antibodies
    4. Inhibition of peroxidase synthesis
    5. Thiocyanate overdose
    1. T4 is transformed to T3 inside the peripheral cell by peripheral deiodinase
    2. T3 is lipid soluble and enters peripheral cells passively
    3. Thyroid hormone receptor in peripheral cells are in the nucleus of the cell
    4. Thyroid hormones require a coactivator
    5. T4 must be converted to T3 by peripheral deiodinase

    Author of lecture Thyroid Hormone Function

     Carlo Raj, MD

    Carlo Raj, MD

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