Lectures

Overview – Antiviral Agents and Treatment of CMV Retinitis – Antiviral Drugs

by Pravin Shukle, MD
(1)

Questions about the lecture
My Notes
  • Required.
Save Cancel
    Learning Material 2
    • PDF
      Slide Anti-Virals Antimicrobials.pdf
    • PDF
      Download Lecture Overview
    Report mistake
    Transcript
    So just as an overview I have here a list of the different agents and which viruses they are particularly active against. And I've listed the primary versus the secondary drugs. So in cyctomegalovirus, the primary drugs are ganciclovir, HSV and VZV. Acyclovir is a primary drug. And hepatitis B virus interferon alpha is a very, very effective treatment. Also hepatitis C we tend to use a lot of interferon alpha. Influenza A, you're probably quite familiar with this agent. You may even have taken it yourself. And also influenza B, it's also quite active as well. Now we're going to talk about some specialized treament issues. Let's talk about CMV retinitis. So we will also cover this in the opthamology portions of our lectures. But just to get the idea of these agents now, in terms of sight threatening lesions that are often found adjacent. For example, to the optic nerve or to the fovea, we will use intravitreal injections of ganciclovir. Sometimes we'll use intravitreal infection of foscarnet as well. Now these are obviously administered by an opthamologist. Now for systemic cytomegalovirus therapy we may use valganciclovir which is -- sorry valganciclovir which is used orally twice a day for up to three weeks. Alternatives include ganciclovir. So intravitreal and systemic therapies are a little bit different. So remember the intravitreal injections are exceedingly effective in CMV retinitis. In terms of peripheral lesions, sometimes we'll use systemic therapy in association with the intravitreal treatment. ...

    About the Lecture

    The lecture Overview – Antiviral Agents and Treatment of CMV Retinitis – Antiviral Drugs by Pravin Shukle, MD is from the course Antimicrobial Pharmacology.


    Author of lecture Overview – Antiviral Agents and Treatment of CMV Retinitis – Antiviral Drugs

     Pravin Shukle, MD

    Pravin Shukle, MD


    Customer reviews

    (1)
    5,0 of 5 stars
    5 Stars
    5
    4 Stars
    0
    3 Stars
    0
    2 Stars
    0
    1  Star
    0