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Male Hypogonadism

by Carlo Raj, MD
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    Our topic is male hypogonadism. What happened here? Well walk through maybe primary hypogonadism. Normal range is about 713, 1300 ng/dL. Take a look at your age, 18 to 29. You want there to quite a bit of testosterone. What then happens after the age of 70? Do you understand this? The fact that if there is any chance of a male becoming infertile, It might be average age of approximately 70. So, during that whole time, not every patient obviously because as I said low-T syndrome is a real thing in clinical practice in the US. Classification: what if it’s a primary testicular dysfunction? What would you call this? We talked about this in previous table. Take your time here. We call this primary hypogonadism. How would you call this pathophysiologically? You would call this hypogonadism. The testis are not functioning properly. You would have increase in LH and FSH, so primary hypogonadism, A.K.A., hypergonadotropic hypogonadism. Clear? Secondary, central. You put together pituitary, hypothalamus. I've told you to do that a number of times, secondary or perhaps tertiary, secondary anterior pituitary, tertiary hypothalamus. If that’s knocked out, what do you call this clinically or pathophysiologically? Hypogonadotropic hypogonadism. Causes of male hypogonadism. Primary: trauma, autoimmune destruction. Do not forget about mumps and microbe, orchitis. Inflammation of the testis, inflammation of the parotid, orchitis, parotitis. Medications: cyclosporine, chemotherapy. Congenital disorders: Well talk about Klinefelter big time and something called bilateral anorchia. In other words, it's the fact that, my goodness gracious, congenital, the testis won’t even properly develop. Primary, why do we call it hypogonadotropic. Are we clear? Do I sound like a broken record yet? Good, I should. You want me to because you want to get bored with what I’m saying because Dr. Raj, I know this. Stop talking....

    About the Lecture

    The lecture Male Hypogonadism by Carlo Raj, MD is from the course Reproductive Hormone Disorders.


    Included Quiz Questions

    1. levels of testosterone decrease to 150-500 in the sixth decade of life.
    2. Normal level of testosterone in 18-29 years old male is 700-1300 ng/dl
    3. In secondary and tertiary hypogonadism LH/FSH levels are abnormally low.
    4. Hypogonadism of the aging man is considered primary hypogonadism.
    5. secondary hypogonadism is a result of pituitary hypofunction
    1. primary
    2. secondary
    3. hypogonadotropic hypogonadism.
    4. tertiary
    5. other
    1. unilateral anorchia
    2. autoimmune orchitis
    3. cyclosporine therapy
    4. mumps orchitis
    5. genital trauma
    1. cyclosporine
    2. prolactinoma
    3. glucocorticoids
    4. opiates
    5. leuprolide
    1. Hemochromatosis
    2. Cryptorchidism
    3. Kallmann syndrome
    4. Klinefelter syndrome
    5. prolactinoma

    Author of lecture Male Hypogonadism

     Carlo Raj, MD

    Carlo Raj, MD


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