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Causes: Immaturity & Pregnancy – Secondary Immunodeficiency Diseases

by Peter Delves, PhD
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    About the Lecture

    The lecture Causes: Immaturity & Pregnancy – Secondary Immunodeficiency Diseases by Peter Delves, PhD is from the course Immunodeficiency and Immune Deficiency Diseases. It contains the following chapters:

    • Immaturity
    • Pregnancy

    Included Quiz Questions

    1. FcRn
    2. FcγRI
    3. FcγRIIb
    4. Poly Ig receptor
    5. FcεRI
    1. Placentally transferred maternal IgG is metabolized while the neonate produces their own IgG
    2. T cells and B cells are naive and slow to react antigens
    3. Immature immune system due to pre-term birth
    4. Lack of innate immunity
    5. Maternal IgG is replaced by IgM
    1. 1 year old
    2. 28 days old
    3. 10 years old
    4. 6 months old
    5. 3 years old
    1. The mother must be immunosuppressed because developing fetus is semi-allogeneic
    2. The mother must be immunosuppressed so that IgG crossing the placenta and being transferred to the fetus does not cause embryologic abnormalities
    3. The mother must be immunosuppressed because the placenta is partially fetal tissue
    4. The mother must be immunosuppressed so that the immune system does not turn against the fetus after being exposed to an endogenous antigen
    5. The mother must be immunosuppressed in order to divert metabolic resources to the developing fetus

    Author of lecture Causes: Immaturity & Pregnancy – Secondary Immunodeficiency Diseases

     Peter Delves, PhD

    Peter Delves, PhD


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