00:00
Now sound waves enter the outer ear
causing the eardrum to vibrate.
00:04
So there is the canal.
00:05
That sound wave comes in.
00:07
And part of the design of the
canal is to sort of focus and
localize that sound information
and bring it right to the outer
-- sorry, to the eardrum.
00:17
Now the vibration passes from the
malleus to the incus to stapes
and it’s, literally, a movement
of bones in this solution.
00:24
And the stapes carries vibrational
information to the oval window.
00:28
At which point, vibrations
is in the oval window
create pressure waves in
the fluid of the cochlea.
00:33
And that’s where we’re really
getting a lot of the activation.
00:36
So all of these previous steps
that I’ve talked about,
the job is to take this information coming
from the air, literally, sound waves,
focus them,
have them go through
an aqueous solution,
that’s the solution
in the cochlea,
and convert that into
vibrational energy.
00:52
And then we get to the third
stage which is converting
these pressure waves into
actual movement of hair cells.
01:00
So the basilar membrane is covered by
these hair cells which have cilia.
01:04
And you move the cilia.
01:06
These structures are found in something
called the organ of Corti.
01:09
And as these little hairs move,
it actually opens ion channel.
01:14
So we say displacement by the wave
opens ion channels which leads to
neurotransmitter release and then
goes on a cause and action potential.
01:21
So again, sound energy gets
converted into wave energy.
01:25
It gets converted into vibrational energy
within the wave into mechanical energy,
movement of the hair cells, which gets
converted into an action potential.
01:34
And also included in there is some
chemical because of the neurotransmitter.
01:38
So we’ve gone through
this whole slew of stuff.
01:40
And that’s why I was saying I want you
to kind of appreciate you hearing
the melodic tones of my voice,
because how much is happening
for you to hear that?
And it doesn’t happen
in a choppy fashion.
01:52
You hear my voice. Everything
seems to make sense.
01:55
There seems to be --
There seems to be an acquisition
of temporal information,
the candor of my speech.
02:01
All of this is happening
through this process.
02:06
Okay, so here’s a blow up
of the basilar membrane.
02:09
So I was mentioning it
contains those hair cells.
02:12
Now the way it’s designed
is it’s actually tapered.
02:14
So the membrane is tapered
and stiffer at the basal end
and wider and floppier
at the apical end.
02:20
So you can see from the diagram,
you kind of have this formation.
02:23
And at the --
At the base, it’s a
little bit stiffer.
02:27
And at the other end, where it’s wider,
it’s floppier, and that allows us to do
something really unique and that
differentiate between different frequencies.
02:35
So the base, which is
closer to the oval window,
we have a higher frequency,
shorter wavelengths.
02:40
And at the apex,
we have --
this is the farthest point
from the oval window.
02:44
That’s where the low frequency
or the longer wavelengths.
02:47
So if you’re thinking to
make this make more sense,
maybe the radio, you have
your treble in your base.
02:52
The treble, which is kind
of the higher pitch sound
that would be encoded
at the base,
whereas the good deep base is going
to be found at the apex.
03:02
Okay, so now if you take a look at the
black and white micrographic at the top,
it shows a blowup of the
actual basilar membrane
and you can see those
little hair cells.
03:12
And in the cartoon below, you
noticed that they’re all lined up
and you can see that they’re
on the basilar membrane
with the base being
narrow, apex being wide.
03:20
You have high frequency,
low frequency.
03:23
You have the treble,
you have the base.