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Overview of Diabetes Mellitus – Hyperglycemia

by Carlo Raj, MD
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    Welcome to the topic of diabetes mellitus. This is the prototype of your endocrine pancreas and what may then go wrong with it. Initially, we’ll go through in great detail the pathogenesis, we will describe in great detail type I and type II diabetes. I’ll walk you through secondary diabetes, meaning to say that, well, was there something else going on with your patient such as haemochromatosis, maybe Cushing’s resulting in hyperglycemia. I’ll walk you next into your complications and finally, a word or two about management of diabetes mellitus. Welcome to hyperglycemia. Diabetes mellitus itself is a chronic disease dealing with carbohydrates, fats and protein metabolism. The fact that the balance of insulin and glucagon in fact has been lost. Maybe there’s issue with a receptor causing or creating an environment of insulin resistance. In any case, your patient with diabetes mellitus will always have hyperglycemia. Therefore, you’ll do everything in your power to make sure that you’re able to prevent the glucose levels from rising to excessive levels. Importantly, you are responsible to be able to diagnose your patient with hyperglycemia. Any one of the three following criteria that you must be familiar with. You wake up in the morning fasting glucose and you find your fasting glucose to be above 126 milligrams per decilitre if… is of outmost importance. If you can then remember upon two separate occasions of finding random plasma glucose above 200 then perhaps you’re suspecting diabetes mellitus. Number two, the symptoms of diabetes… P, P, P… polyuria, polydipsia, polyphagia. All these glucose that’s in your circulation ends up in your renal, your nephron bringing about osmotic diuresis thus polyuria. All the urination is then making you feel thirsty… polydipsia. And thirdly, without proper uptake of glucose in your tissue, wow, you’re always feeling...

    About the Lecture

    The lecture Overview of Diabetes Mellitus – Hyperglycemia by Carlo Raj, MD is from the course Pancreatic Disease & Diabetes.


    Included Quiz Questions

    1. Hyperglycemia
    2. Increased cortisol
    3. Hypercalcemia
    4. Uremia
    5. Increased fat deposition
    1. Symptoms of diabetes with a random glucose > 200mg/dL
    2. Polyuria, polydipsia, and polyphagia with a random glucose > 100mg/dL
    3. Plasma glucose > 200mg/dL 24 hours after an oral glucose load
    4. Fasting glucose > 120mg/dL on two separate occasions
    5. Random glucose > 300mg/dL on one occasion
    1. 7%
    2. 5%
    3. 10%
    4. 3%
    5. 12%
    1. Fasting glucose of 110mg/dL
    2. Fasting glucose of 90mg/dL
    3. Plasma glucose of 125mg/dL 2 hours after glucose load
    4. Fasting glucose of 135mg/dL
    5. Plasma glucose of 210mg/dL 2 hours after glucose load

    Author of lecture Overview of Diabetes Mellitus – Hyperglycemia

     Carlo Raj, MD

    Carlo Raj, MD


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