Lectures

B-Cell Development in the Bone Marrow – Lymphocyte Development

by Peter Delves, PhD
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    About the Lecture

    The lecture B-Cell Development in the Bone Marrow – Lymphocyte Development by Peter Delves, PhD is from the course Adaptive Immune System. It contains the following chapters:

    • B-Cell Development in the Bone Marrow
    • Anatomic Site of the B-Cell Development

    Included Quiz Questions

    1. λ5
    2. λ4
    3. λ3
    4. λ2
    5. λ1
    1. Pro-B to Pre-B
    2. Stem cell to Pro-B
    3. Pre-B to Immature B
    4. Immature B to Mature B
    5. Pre-B to Pro-B
    1. Pre-B
    2. Stem Cell
    3. Pro-B
    4. Immature B
    5. Mature B
    1. Recombination of both the light and heavy chain regions of the antibody molecule
    2. Cytoplasmic μ combines with cytoplasmic κ
    3. Light chains differentiate into either μ or λ
    4. Recombination in both the Stem cell and Pro-B cell stages
    5. Pre-B cell must encounter an antigen in order for the antibody molecule to mature
    1. Mature B cells in circulation but no production of B cell precursors
    2. Pro-B and Pre-B cell proliferation with few to no Mature B cells
    3. Many Stem cells with few B cell precursors
    4. Immature B cells that cannot progress to Mature B cells
    5. Pro-B cells that cannot progress to Pre-B cells with mature antibody molecules
    1. Surrogate light chains
    2. Surface IgM with κ light chains
    3. Surface IgM with λ light chains
    4. Surface IgM and Surface IgD
    5. μ heavy chains

    Author of lecture B-Cell Development in the Bone Marrow – Lymphocyte Development

     Peter Delves, PhD

    Peter Delves, PhD


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