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Asthma: Introduction

by Carlo Raj, MD
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    00:02 Let's take a look at obstructive lung diseases and our first true pathology here, under obstructive, we’ll take a look at asthma. Keep in mind that much of this information in terms of its pathogenesis comes from immunology. So our strict focus here is going to be our patient, how are they going to present, and then ultimately, tie this in with the other obstructive diseases in which often times may be confused with emphysema and chronic bronchitis.

    00:29 Let’s begin. Asthma, inflammatory disease, small airway. Inflammation to airway, that leads to what? Mucous production. Stop there. I told you at some point in time that we will take a look at the definition here versus definition of chronic bronchitis. Why do I bring chronic bronchitis into play? Because of mucous production. Chronic bronchitis however, represents the fact that your patient is presenting with 3 months of continuous productive cough over a 2 year span. Bronchospasm, leading to a reversible obstructive lung disease. Well, it depends. But for the most part, think of it as being reversible.

    01:11 Why? Well, if you’re able to relieve your patient of whatever exposure that the patient might be having resulting in the asthma type attack, maybe perhaps you are able to reverse it. That’s an important definition there. Bronchodilators come to mind.

    01:28 Usually and typically seen in young patients. Many asthma patients usually end up having or have had exposure to allergen. This puts you in the realm of something like atopic which is majority of your patients with asthma or they’ve had a viral, URI stands for upper respiratory tract infections. Now all these can be exacerbated with having asthma.

    01:54 Now, what’s going on here actually? Well this comes under obstructive so imagine that increased mucous production taking place in the airway. Take a look at the first picture up above. And if it is, then you’re having a hard time then with exhalation. Take a look at the bottom picture here, the airways then filled with mucous.

    02:14 So, in other words, it’s airway reactive disease, isn’t it? Bronchospasms. Now, if you want to keep these airways open then you tell me as to what kind of receptor these would then act upon or what kind of drug or perhaps your adrenergic agents would act upon in which it would then bring about bronchodilation? Good, Beta2.

    02:36 Increased smooth muscle tone, narrowing your airways is now a problem, increased inflammation, edema further causes narrowing and may result in plugs and these plugs make it difficult for you to do what? Good, difficulty with exhalation. How is the patient going to sound? Wheezing, wheezing way down in the alveoli. Keep that in mind.

    03:01 Asthma is an obstructive, expiratory disease as noted, patients will have episodic wheezing,


    About the Lecture

    The lecture Asthma: Introduction by Carlo Raj, MD is from the course Obstructive Lung Disease.


    Author of lecture Asthma: Introduction

     Carlo Raj, MD

    Carlo Raj, MD


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    Embarrassing for lecturio
    By Patrick C. on 11. April 2018 for Asthma: Introduction

    Horrible. Whats even more horrible is that there are previous comments written months ago and Lecturio could care less to correct them. Great job Lecturio in keeping your paying customers happy. Waste of money.

     
    Impossible to understand
    By Manraj J. on 23. February 2018 for Asthma: Introduction

    The lecture is incredibly incoherent, lacks sentence structure and doesn't really make sense

     
    Explanation is not coherent, does not use full sentences, connections between concepts are not logical. Does not articulate.
    By Nicole G. on 30. January 2018 for Asthma: Introduction

    Explanation is not coherent, does not use full sentences, connections between concepts are not logical. Does not articulate.