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Case Study – Antiviral Drugs

by Pravin Shukle, MD
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    Let's move on to some questions. A 63 year old hemophiliac had contracted hepatitis B from contaminated blood products in the 1980's. He stopped his medications against medical advice three months ago. And presents now with fulminant transaminitis and jaundice. The following are true statements about Hepatitis B in medications. A. Interferon alpha acts through tyrosine kinase receptors. B. Interferon alpha is quickly absorbed at the injection site. C. Interferon alpha inhibits ribonuclease that degrades viral messengerRNA. And D. Interferon alpha promotes the formation of natural killer cells. So find the true statement. Fantastic, you picked D. Interferon alpha promotes the formation of natural killer cells. Let's move on to the next question. A 45 year old male has contracted influenza B. The following statements are true: A. Zamanivir is an intranasal spray that may be beneficial for this patient if taken within 24 hours of the onset of symptoms. B. Amantadine may be used as a prophylaxis for this patient. C. Rimantadine may be beneficial for this patient if taken within 24 hours of the onset of symptoms. D. Amantadine is an inhibitor of neuraminidase. or E. Zamanivir which acts through blockage of a proton port in the cell wall that prevents acidification of the interior of the virus. The answer is A. Zamanivir is an intranasal spray that may be beneficial for this patient if taken within 24 hours of the onset of symptoms. D is incorrect because amantadine is a blocker of a proton pump in the vesicle wall, that would have allowed transcription with an acidic environment. E is incorrect because zamanivir is a neuraminidase inhibitor. It does not act on a proton port. Therefore, the correct answer is A. Let's go on to another question. A 34 year old male represents with a painful left...

    About the Lecture

    The lecture Case Study – Antiviral Drugs by Pravin Shukle, MD is from the course Antimicrobial Pharmacology.


    Author of lecture Case Study – Antiviral Drugs

     Pravin Shukle, MD

    Pravin Shukle, MD


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