Acute and Chronic Diabetes Complications

by Carlo Raj, MD

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    Now that we established the definition of hyperglycemia and all the differentials we’ve looked at, let us now take a look at complications specifically for type I and type II diabetes. We will organize our complications initially with acute and chronic and as we move forward, we will then take a look at some of these issues and complications in much greater detail. With acute complication type I diabetes, if not controlled properly, the patient maybe in a state of ketoacidosis. Remember that this would be an endogenous production of keto acids, therefore would be referred to as being or experiencing metabolic acidosis with an anion gap, which we shall refer to. Type II diabetes mellitus, if untreated, complications here acutely rarely would it be diabetic ketoacidosis, but it would be hyperosmolar, hyperglycemic state or sometimes worst case scenario hyperosmolar, hyperglycemic type of coma, but it would be non-ketotic. The reason in type II diabetes to be non-ketotic is because there might be residual amounts of insulin and just enough insulin and make sure that your biochemistry is strong here, that if you have just enough insulin that you may not be forced to break down your lipid and have beta oxidation taking place. So, therefore, the hyperosmolar is being caused by the hyperglycaemia in type II diabetes if it’s uncontrollable. Remember all these mellitus and now that we’re doing medicine, let’s be a little bit more technical versus insipidus. Remember that in insipidus, you will have and mellitus, you would have both polydipsia and polyuria. However, in insipidus, you would not have polyphagia. Our focus beyond acute is chronic complications. The chronic complications would be quite similar for both type I and type II diabetes mellitus if left untreated or poorly controlled. If it’s type I diabetes, then the...

    About the Lecture

    The lecture Acute and Chronic Diabetes Complications by Carlo Raj, MD is from the course Pancreatic Disease & Diabetes.

    Included Quiz Questions

    1. Lack of production of ketones
    2. Increased acidosis
    3. Decreased insulin
    4. Lack of production of insulin
    5. Lack of anion gap in the metabolic acidosis
    1. Cerebrovascular disease
    2. Neuropathy of entire hand
    3. Retinopathy
    4. Nephropathy
    5. Neuropathy of entire foot
    1. Microvascular- hyaline arteriosclerosis
    2. Macrovascular- hyaline arteriosclerosis
    3. Microvascular- atherosclerosis
    4. Macrovascular- sorbitol excess
    5. Microvascular- sorbitol excess

    Author of lecture Acute and Chronic Diabetes Complications

     Carlo Raj, MD

    Carlo Raj, MD

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