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Acute Bacterial Meningitis: Predisposing Factor Age

by Carlo Raj, MD
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    00:01 Here’s another table for you.

    00:02 What do know about these tables? Money! What does that mean? It means that you need to make sure you take these tables and get a good understanding.

    00:10 Your minor information that is in this table, if you truly understand your pathology, these tables speak volumes to you.

    00:18 You can use these in pathology, pharmacology, microbiology, so on and so forth.

    00:22 So here, the topic is still acute bacterial meningitis, okay? Strictly bacterial.

    00:29 Tell me about glucose in your cerebrospinal fluid.

    00:31 High or low? Low.

    00:34 Protein content: High or low in the CSF? High.

    00:38 Your WBCs, well, granted, WBC would be elevated in any type of meningitis.

    00:45 But here, it’s specifically – What kind of WBC would you expect to see in bacterial? Good.

    00:50 Neutrophils.

    00:51 Okay.

    00:52 Now, based on that, what are the parameters that we’re looking at here? We have the predisposing factors in terms of age.

    00:58 And then depending, on the age, we’ll talk about the most common bacterial pathogen.

    01:02 And then quickly, we’ll take a look at management commonly for antimicrobial therapy.

    01:08 Less than one month, what are your organisms? Your CAMP-positive Streptococcus agalactiae.

    01:14 Agalactiae, memorize that.

    01:16 E. coli, gram-negative organism.

    01:18 Listeria, at least know those three organisms causing acute bacterial meningitis in a child less than one month.

    01:28 Antimicrobial therapy.

    01:29 This keeps changing, but for the most part, you have ampicillin being a common denominator plus cefotaxime or maybe perhaps aminoglycoside.

    01:38 Now, what’s an interesting point that the boards love to ask and clinically that you need to make sure that if you’re getting questioned by your attending and you want to make sure that you’re well-versed with, let’s say, drug interactions, 1 – 23 months in hour getting close to 2 years. What kind of organisms you are looking at here? Still streptococcus mainly perhaps. But this time its pneumonia.

    02:01 Neisseria is [00:02:03,9] its ugly head here. And you still have agalactiae And we have a new comer And that would be our haemophilus influenza.

    02:12 Keep that in mind but I want to make sure that you are clear.

    02:16 Step back for one second the haemophilus influenza will be the virus I apologize for putting this under bacteria but I like to put this seriously that you have common organisms that cause acute meningitis with H.

    02:30 Here if you are thinking about the this age group maybe perhaps the vancomycin And we have a little bit later.

    02:38 A little bit later meaning what? The two extreme ages of life.

    02:45 Very young and very old.

    02:48 For this row, very young, very old.

    02:51 With streptococcus pneumoniae and there is this species Once again vancomycin.

    02:56 And then greater than 50 you should be thinking about streptococcus pneumoniae And maybe perhaps your Listeria monocytogenes.

    03:04 Alright, so we are getting to old once again. A vancomycin plus ampicillin And then you have a plus third generation.

    03:11 So here’s the general overview as to when you can expect in terms of common pathogens All of these are all bacterial, okay.


    About the Lecture

    The lecture Acute Bacterial Meningitis: Predisposing Factor Age by Carlo Raj, MD is from the course CNS Infection—Clinical Neurology.


    Included Quiz Questions

    1. Listeria Monocytogens
    2. Streptococcus pneumoniae
    3. Hemophilus influenzae
    4. Neisseria meningitidis
    5. Aerobic gram-negative bacilli
    1. Sulphonamides
    2. Ampicillin
    3. Cefotaxime
    4. Aminoglycosides
    5. Vancomycin
    1. It causes Kernicterus.
    2. It causes Steven Johnsons syndrome.
    3. It can cause severe rashes.
    4. It can cause liver dysfunction.
    5. It can cause Reye Syndrome.
    1. Unconjugated bilirubin
    2. Conjugated bilirubin
    3. Sulfur moieties
    4. Folic acid
    5. Iron

    Author of lecture Acute Bacterial Meningitis: Predisposing Factor Age

     Carlo Raj, MD

    Carlo Raj, MD


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