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Número Necesario a Tratar

El número necesario a tratar ( NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat) es el número de pacientes que se necesitan tratar para prevenir 1 resultado secundario adicional (e.g., accidente cerebrovascular, muerte). Por ejemplo, si un medicamento tiene un NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat de 10, significa que 10 personas deben recibir tratamiento con el medicamento para prevenir 1 resultado secundario adicional. El NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat es el inverso de la reducción del riesgo absoluto (RRA), que es igual a la tasa de resultados secundarios que ocurren en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el grupo de control menos la cantidad de resultados secundarios en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el grupo experimental.

Last updated: Dec 15, 2025

Editorial responsibility: Stanley Oiseth, Lindsay Jones, Evelin Maza

Definición

El número necesario a tratar ( NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat); y su análogo, el número necesario para dañar (NND), son simplemente otras medidas del tamaño del efecto, como la d de Cohen, y ayudan a relacionar una diferencia en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el tamaño del efecto con la relevancia clínica del mundo real.

Número necesario a tratar

El NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat significa cuántos pacientes necesitarían ser tratados para mejorar el estado de 1 paciente adicional, que de otro modo no habría mejorado sin ese tratamiento en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum particular.

  • El inverso de la reducción de riesgo absoluto (RRA) = 1/RRA
  • El NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat es un número entre 1 e infinito:
    • Un número más bajo indica un tratamiento más efectivo.
    • Las fracciones se redondean al AL Amyloidosis siguiente número entero.
    • Un NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat perfecto sería 1, lo que significa que por cada paciente tratado, 1 mejoró en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el ensayo, que no habría mejorado sin ese tratamiento específico.

Reducción de riesgo absoluto, diferencia de riesgo absoluto (DRA) y exceso de riesgo absoluto (ERA)

Todos estos términos representan el valor absoluto de la diferencia entre la proporción (expresada como porcentaje, fracción o incidencia) de pacientes en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el grupo control (Pc) que tuvieron el resultado de interés y la proporción de pacientes en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el grupo experimental (Pe) con eso el resultado de interés:

$$ {RRA = DRA = ERA = \left | P_{c} – P_{e} \right |} $$

Características e Interpretación

Características

  • Debe interpretarse en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum contexto: una estimación puntual de NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat aislada tiene poco valor, aunque aproximadamente el 50% de los LOS Neisseria estudios clínicos no proporcionan la información contextual necesaria.
  • El NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat utiliza la RRA y no la reducción de riesgo relativo ( RRR RRR Measures of Risk), que tiende a enfatizar demasiado el beneficio.
    • RRR RRR Measures of Risk = (Pe – Pc)/Pc.
    • Por ejemplo, si el riesgo inicial fuera del 0,2% y el medicamento X redujera este riesgo al AL Amyloidosis 0,1%, la RRR RRR Measures of Risk seguiría siendo del 50%, pero la RRA sería solo del 0,1%, lo que no es una gran diferencia con respecto a la línea de base.
    • Como la RRR RRR Measures of Risk está directamente correlacionada con la RRA, el NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat también está inversamente correlacionado con la RRR RRR Measures of Risk.
  • El NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat le dice cuántos pacientes se beneficiarían, pero no cuánto se pueden beneficiar. Las respuestas a las siguientes preguntas deben proporcionarse con el NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat para poder interpretarlo completamente:
    • ¿Cuál es el riesgo inicial de los LOS Neisseria pacientes en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el estudio?
    • ¿Cuál es el comparador? (e.g., ¿ningún tratamiento?, ¿ placebo Placebo Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol. Epidemiological Studies?, ¿otra terapia?)
    • ¿Cuál es el resultado? (e.g., ¿curación completa?, ¿mejora del 30%?)
    • ¿Cuánto dura el estudio? (debe incluirse con el NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat)
    • ¿Qué es el intervalo de confianza?

Interpretación

  • Cuanto menor sea el NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat, mejor; cuanto mayor sea el NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat, menos personas recibirán ayuda.
  • Las intervenciones de tratamiento que tienen un NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat de uno o dos dígitos bajos generalmente se consideran efectivas para tratar afecciones sintomáticas.
  • Para los LOS Neisseria resultados con una importancia clínica alta, como la prevención de la muerte, también se puede considerar útil un NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum los LOS Neisseria 100 inferiores.
  • Para las terapias preventivas, los LOS Neisseria NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat también pueden ser altos.

Número Necesario Para Dañar

El NND es el número adicional de personas que necesitan estar expuestas al AL Amyloidosis riesgo (exposición dañina o tratamiento) para que 1 persona adicional desarrolle la enfermedad en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum comparación con el grupo no expuesto.

  • El NNH NNH The NNH is the additional number of individuals who need to be exposed to risk (harmful exposure or treatment) to have 1 extra person develop the disease compared to that in the unexposed group. Number Needed to Treat es el inverso del ERA (1/ERA).
  • La relación entre NND y NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat: Un NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat negativo indica que el tratamiento tiene un efecto nocivo. Por ejemplo, un NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat de −10 indica que si 10 pacientes son tratados con el nuevo tratamiento, una persona adicional se vería perjudicada en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum comparación con los LOS Neisseria pacientes que reciben el tratamiento estándar, i.e., el NND = 10.
  • Al AL Amyloidosis igual que el NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat, el NND debe interpretarse en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum contexto.

Cálculo del NNT y NND

La base para calcular el NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat y NND

Una tabla de contingencia de 2 x 2 usa un resultado binario y 2 grupos de sujetos para mostrar la base para calcular NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat y NND. Cada resultado debe expresarse como una proporción, porcentaje o incidencia, y no como el número real de sujetos.

Resultado Grupo tratado Grupo control
Positivo a b
Negativo c d
Total a + c b + d
Esta tabla de contingencia de 2 x 2 usa un resultado binario y 2 grupos de sujetos para mostrar la base para calcular el NNT y NND. Cada resultado debe expresarse como una proporción, porcentaje o incidencia, y no como el número real de sujetos.
NNT: número necesario a tratar
NND: número necesario para dañar

Si lo siguiente es cierto, la diferencia de proporciones es P tratado – P control.

  • P tratado = la proporción de sujetos con un resultado positivo en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el grupo tratado
  • P tratado = a/(a + b)
  • P control = la proporción de sujetos con un resultado positivo en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el grupo control
  • P control = b/(b + d)

La diferencia de riesgo absoluto (DRA) es igual a la RRA, que se calcula como el valor absoluto de la diferencia entre P tratado y P control.

$$ {DRA = RRA = \left | P_{tratado} – P_{control} \right |} $$

Entonces, el NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat se puede calcular como:

$$ {NNT = \frac{1}{\left | P_{tratado} – P_{control} \right |}} $$

Si el grupo tratado o expuesto tiene un peor resultado que el control, la RRA se llama ERA. En EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum ese caso, el NNT NNT The number needed to treat (NNT) is the number of patients that are needed to treat to prevent 1 additional adverse outcome (e.g., stroke, death). For example, if a drug has an nnt of 10, it means 10 people must be treated with the drug to prevent 1 additional adverse outcome. Number Needed to Treat se llama número necesario para dañar (NND). En EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum ambos casos, el cálculo es el mismo (NND = 1/DRA).

Preguntas de Práctica

Un ensayo clínico aleatorizado estudió el efecto de la exposición infantil al AL Amyloidosis humo de 2da mano sobre la incidencia de adenocarcinoma broncogénico. El estudio incluyó a 100 sujetos (50 expuestos al AL Amyloidosis humo de 2da mano en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la infancia y 50 controles sanos sin exposición en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la infancia) e involucró el seguimiento de la incidencia de adenocarcinoma broncogénico a lo largo de la vida. Los LOS Neisseria datos del estudio se muestran en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la siguiente tabla:

Resultado Grupo Expuesto Grupo Control
Adenocarcinoma broncogénico presente 18 7
Adenocarcinoma broncogénico no presente 32 43
Total 50 50

Pregunta 1

¿Qué es el NND?

Respuesta: NND = 1/diferencia de riesgo absoluta (llamada “ERA” cuando se trata de NND). ERA = Pe – Pc = 18/50 – 7/50 = 0,22. NND = 1/0,22 = 4,45 ⇾ 5, lo que significa que 5 personas deben estar expuestas al AL Amyloidosis humo de 2da mano en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la infancia para que 1 persona adicional desarrolle adenocarcinoma broncogénico en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum comparación con el grupo no expuesto.

Pregunta 2

¿Cuál es el aumento de riesgo relativo en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum el estudio citado en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la Pregunta 1?

Respuesta: El aumento del riesgo relativo = (Pe – Pc)/Pc = (18/50 – 7/50)/7/50 = 1,57, lo que significa que las personas expuestas al AL Amyloidosis humo de 2da mano en EN Erythema nodosum is an immune-mediated panniculitis (inflammation of the subcutaneous fat) caused by a type IV (delayed-type) hypersensitivity reaction. It commonly manifests in young women as tender, erythematous nodules on the shins. Erythema Nodosum la infancia tienen 1,57 veces más probabilidades de desarrollar adenocarcinoma broncogénico después de la exposición al AL Amyloidosis humo de 2da mano que los LOS Neisseria que no estuvieron expuestos.

Referencias

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