Yolk Sac Tumor (Endodermal Sinus Tumor)

by Carlo Raj, MD

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    00:01 We’ll go into another type of germ cell tumor.

    00:04 You should know both names, endodermal sinus tumor, a.k.a. yolk sac, and stop there.

    00:10 Allow the name to speak to you.

    00:11 Yolk sac.

    00:12 A little baby.

    00:13 Okay? And what I mean by that is the fact the most common -- most common ovarian tumor in a girl less than five years of age, Yolk sac tumor, a.k.a. endodermal sinus.

    00:26 Rare second most tumor of germ cell origin, resembles yolk sac.

    00:32 Here, you’ll find increase levels of alpha fetoprotein and the glomerulus-like structure composed of central blood.

    00:39 It’s exactly what you would be seeing in histologic picture.

    00:43 This is then referred to as Schiller–Duval body.

    00:48 You have a Schiller–Duval body which resembles a glomeruli.

    00:52 This is used to represent your yolk sac or endodermal sinus.

    00:55 Your patient here are boys and girls.

    About the Lecture

    The lecture Yolk Sac Tumor (Endodermal Sinus Tumor) by Carlo Raj, MD is from the course Ovarian Diseases.

    Included Quiz Questions

    1. Alpha-fetoprotein (AFP)
    2. CA 15-3
    3. CA 19-9
    4. Carcinoembryonic antigen (CEA)
    5. Human chorionic gonadotropin (hCG)

    Author of lecture Yolk Sac Tumor (Endodermal Sinus Tumor)

     Carlo Raj, MD

    Carlo Raj, MD

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